Influenza {50002710} Record Keys Parent:[ ] Definition:Influenza Details Initialisation date:[ ] Meta Information Rank:[ ] Domain:[ ] Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Covid-19] [#Human adenovirus, #Human coronavirus] [#Short Chain Fatty Acid] - Increased abundance of SCFA-producing bacteria appears to offer protection against many common respiratory viruses including #Rhinovirus, #Respiratory syncytial virus, adenovirus, influenza and severe acute respiratory syndrome #Coronavirus 2 (SARS-CoV-2) [1.2] - #High ambient temperature of 36 °C increases host resistance to viral pathogens including influenza virus and severe acute respiratory syndrome #Coronavirus 2 (SARS-CoV-2). - High heat-exposed mice increase basal body temperature over 38 °C to enable more #Bile Acids production in a gut microbiota-dependent manner. - The gut microbiota-derived #Deoxycholic acid (DCA) and its plasma membrane-bound receptor Takeda G-protein-coupled receptor 5 (TGR5) signaling increase host resistance to influenza virus infection by suppressing virus replication and neutrophil-dependent tissue damage. - the DCA and its nuclear farnesoid X receptor (FXR) agonist protect Syrian hamsters from lethal SARS-CoV-2 infection. certain #Bile Acids are reduced in the plasma of COVID-19 patients who develop moderate I/II disease compared with the minor severity of illness group. [1.3] [#Respiratory syncytial virus] - dietary polyphenol, lignan and #Phytosterol intake in reducing #Covid-19 risk. - The antiviral efficacy of #Polyphenols including #Lignans and plant sterols has been confirmed against SARS-CoV, MERS-CoV, Ebola virus, HIV, influenza virus and other viruses causing respiratory tract infections. - their beneficial effects against the SARS-CoV-2 virus resulting from their ability to bind to peak protein sites on the ACE2 receptor used by SARS-CoV-2 to infect cells, regulate ACE2 expression and also interfere with SARS-CoV-2 replication by inhibiting the virus protease or inhibiting SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) [1.4] [#Antibiotic Therapy] - antibiotic treatment prior to H1N1 vaccination altered the microbial diversity, resulting in decreased influenza-specific IgG1 and IgA antibody titersReferences Notes[ ]
