Klebsiella aerogenes {50002624} Record Keys Parent:[ ] Definition:Klebsiella aerogenes Details Initialisation date:[ ] Meta Information Rank: Species Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Irritable bowel syndrome] - Bacterial #Histamine acts by attracting mast cells to the colon through activation of the #Histamine 4 receptor. - Klebsiella aerogenes, present in the gut microbiota of many patients with IBS, as the main bacterial producer of #Histamine. [1.2] [#Postmenopausal] - #Estradiol-degrading Klebsiella aerogenes from the feces of premenopausal females with #Depression > In mice, gavaging with this strain led to #Estradiol decline and #Depression-like behaviors. - The gene encoding the #Estradiol-degrading enzyme in K. aerogenes was identified as 3β-hydroxysteroid dehydrogenase (3β-HSD). - The prevalence of K. aerogene and 3β-HSD was higher in premenopausal women with #Depression than in those without #Depression.References Notes[ ]