Gingerols {90000584} Record Keys Parent:[ ] Definition:Gingerols Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Ginger] - Among all the gingerols, 6-gingerol is the most abundant and potent anti-oxidant that yields the greatest anti-inflammatory effects. - A combination of gingerols and #Shogaols is more effective in decreasing inflammatory mediators than the individual compounds [#Neuropathic Pain] [#Shogaols] - Administration of #Ginger root extract or its individual bioactive compound (e.g., 6-gingerol, 6-shogaol, 8-shogaol) has also shown to mitigate pain in animals with SNI-induced NP [1.2] [#Systemic lupus erythematosus, #antiphospholipid syndrome] [#Antimicrobial peptides] - 6-gingerol, the most abundant bioactive phytochemical in #Ginger root, inhibited neutrophil phosphodiesterase (PDE) activity, boosting intracellular cyclic AMP (cAMP) levels and thereby counteracting neutrophil hyperactivity in mouse models of APS and lupusReferences Notes[ ]
