Human milk lipids ⇒ Gangliosides {90000421}

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Shared Reference Notes

  • [1.1] [#Bifidobacterium infantis] [#Human milk lipids] [#Human breast milk
    - Gangliosides are not antagonistic to all gastrointestinal microorganisms. - Bifidobacterium can grow in the presence of GM-3 and GD-3 while simultaneously lowering ganglioside levels in vitro. - #Bifidobacterium bifidum is very efficient in removing GD-3 by employing extracellular mechanisms, while #Bifidobacterium longum subsp. infantis degrades GM-3 intracellularly, with overall lower glycosidase activity.
  • [#Human milk lipids] [#Human breast milk] - The most abundant gangliosides in human milk are monosialoganglioside-3 (GM-3) and disialoganglioside-3 (GD-3). - GD-3 is very abundant in colostrum, while GM-3 increases in abundance at later time points

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