Indoxyl-3-sulfate {90000337} Record Keys Parent:[ ] Definition:Indoxyl-3-sulfate Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - In the liver, #Indole may be metabolized into indoxyl sulfate, which can be toxic in high concentrations. [1.2] [#CVD] - Indoxyl sulfate could promote vascular inflammation. [1.3] [#Indole-3-acetic acid, #Pyruvic acids] - #AHR, especially in barrier tissues of the respiratory and gastrointestinal, can also be activated by dietary and microbial indole-derived metabolites such as pyruvic acid (IPyA), indole acetic acid (IAA), indoxyl-3-sulfate, #Indole-3-carbinole (I3C), and 3,3′-di-indolylmethane (DIM).References Notes[ ]
