Propionate ⇒ Indole-3 propionate {90000334} Record Keys Parent:Propionate Definition:Indole-3 propionate Queue:[ ] Details Initialisation date:2022-08-07 Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:Neurodevelopment, Neuroprotector Notes: [ ]Shared Reference Notes [1.1] [#Indolepropionate] - Intermittent #Fasting promotes axonal regeneration after sciatic nerve crush in mice through an unexpected mechanism that relies on the gram-positive gut microbiome and an increase in the gut bacteria-derived metabolite indole-3-propionic acid (IPA) in the serum. IPA production by #Clostridium sporogenes is required for efficient axonal regeneration, and delivery of IPA after sciatic injury significantly enhances axonal regeneration, accelerating the recovery of sensory function.References Notes[ ]
