Indolepropionate {90000264} Record Keys Parent:[ ] Definition:Indolepropionate Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Para-cresol] - p-cresol derivatives and the tryptophan breakdown product indolepropionate, associated with the gut microbiome. [1.2] [#Indole-3 propionate] - Intermittent #Fasting promotes axonal regeneration after sciatic nerve crush in mice through an unexpected mechanism that relies on the gram-positive gut microbiome and an increase in the gut bacteria-derived metabolite indole-3-propionic acid (IPA) in the serum. IPA production by #Clostridium sporogenes is required for efficient axonal regeneration, and delivery of IPA after sciatic injury significantly enhances axonal regeneration, accelerating the recovery of sensory function. [1.3] [#Diabetes Type 2] - Metabolites associated with the identified fiber-related bacteria (Both #Butyrivibrio and #Faecalibacterium) , including several microbial metabolites (eg, indolepropionate and #3-phenylpropionate) inversely associated with the risk of T2D. References Notes[ ]
