IL-17A {60000086}
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| Definition: | IL-17A |
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| Initialisation date: | 2020-10-04 |
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| Specification: | |
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| Structural Type: | [ ] |
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| Functional Type: | [ ] |
| Function: | Pro-inflammatory |
Notes:
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Shared Reference Notes
- [1.1]
- IL-17A is expressed in mucosal cells and contributes to intestinal homeostasis but might promote inflammation in excess. - IL-17A is mainly produced by Th17 cells. It can also be produced by γδ T cells, natural killer (NK) T cells, macrophages, neutrophils, and eosinophils, but their regulation of IL-17A expression is different. - IL-17 molecules from the gut can influence autoimmune diseases in the central nervous system by regulating the gut microbiota rather than directly triggering brain inflammation
References Notes
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