Muramyldipeptides {90000726}

Record Keys


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Definition:
Muramyldipeptides
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Details


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Meta Information


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Shared Reference Notes


  • [1.1] [#Secreted antigen A
    - MDPs generated by SagA could also increase anti-tumor immunity and improve #Cancer immunotherapy outcomes
  • [#Enterococcus faecium] [#Peptidoglycan] - E. faecium protects the gut from infections by releasing a hydrolase enzyme called #Secreted antigen A (SagA), which is involved in remodeling its cell wall. - SagA breaks down peptidoglycans, the main component of the E. faecium cell wall, to produce small fragments called muramyldipeptides. - These MDPs activate receptors known as NOD2 in the host’s immune cells, leading to improved immunity in the gut.

References Notes


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Common References


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