Secreted antigen A {90000725} Record Keys Parent:[ ] Definition:Secreted antigen A Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Muramyldipeptides] - MDPs generated by SagA could also increase anti-tumor immunity and improve #Cancer immunotherapy outcomes [#Enterococcus faecium] [#Peptidoglycan] - E. faecium protects the gut from infections by releasing a hydrolase enzyme called secreted antigen A (SagA), which is involved in remodeling its cell wall. - SagA breaks down peptidoglycans, the main component of the E. faecium cell wall, to produce small fragments called #Muramyldipeptides. - These MDPs activate receptors known as NOD2 in the host’s immune cells, leading to improved immunity in the gut.References Notes[ ]
