Adenosine {90000470} Record Keys Parent:[ ] Definition:Adenosine Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Pantothenic acid] - At the metabolic pathway level, negative emotions were inversely related to the biosynthesis of pantothenate, #Coenzyme A, and adenosine. [1.2] - #Covid-19 > increased levels of triacylglycerols, phosphatidylcholines, prostaglandin E2, #Arginine, and decreased levels of #Betaine and adenosine in patients with abnormal pulmonary function. [1.3] [#Ruminococcus gnavus] - R. gnavus is capable of producing #Tryptamine, which can affect gut motility through several mechanisms. - First, #Tryptamine activates the #Serotonin receptor 4 (SR4) or #5-hydroxytryptamine receptor 4 (5-HT4R), leading to an increase in intracellular cyclic adenosine monophosphate (cAMP) concentration > This elevation in cAMP levels can enhance gut motility. - Second, #Tryptamine can also increase fluid secretion by acting on the cystic fibrosis transmembrane regulator (CFTR) > promotes the secretion of fluids into the gut, affecting gut motility. [1.4] [#Short Chain Fatty Acid] - The activation of G-protein-coupled receptors by SCFAs triggers the release of peptide YY and #GLP-1, contributing to feelings of satiety and reduced food intake. - SCFAs activate adenosine monophosphate-activated protein kinase, promoting hepatic autophagy and lipid oxidation.References Notes[ ]