Mucin glycans {90000244} Record Keys Parent:[ ] Definition:Mucin glycans Queue:[ ] Details Initialisation date:2022-01-13 Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Human breast milk] - Human milk and mucin glycans show similar molecular characteristics and sugar code. [1.2] [#Parkinson’s Disease] - the upregulated #Threonine pathway, utilize protein sources derived from diet or the host, including mucin. Mucin is an important component of the protective gut mucus layer. Increased capacity to degrade host mucin raises the possibility that the gut microbiome contributes to the degradation and increased permeability of the gut barrier in PD [1.3] - helminth-induced type 2 immune responses in the mammalian host > to alter intestinal bacterial communities via a number of mechanisms, including (1) increased production of SPRR2A and Relmβ proteins that exert antimicrobial activity against gram-positive and gram-negative bacterial spp, respectively, and (2) increased and altered production of mucins. [1.4] [#Polysaccharide] - #Bacteroides thetaiotaomicron can switch from digesting dietary #Glycans to mucin #Glycans in the absence of dietary carbohydrates and plant polysaccharides (dietary fiber), enhancing mucosal barrier function and limiting pathogen invasion.References Notes[ ]
