Corynebacterium ⇒ Corynebacterium accolens {10001076} Record Keys Parent:Corynebacterium Definition:Corynebacterium accolens Details Initialisation date:2022-03-15 Meta Information Rank: Species Domain: Bacteria Zone: Oronasal Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Covid-19] - Corynebacterium accolens is a common nose inhabitant - Corynebacterium accolens incidence was significantly decreased in the URT of patients with SARS-CoV-2 compared with uninfected controls. Corynebacterium accolens can inhibit Streptococcus pneumoniae and Staphylococcus aureus growth, possibly through triolein hydrolysis, which releases #Oleic acid. - In addition to inhibiting bacterial pathogens, #Oleic acid is capable of inhibiting other enveloped viruses, such as herpes and influenza. - Oleoylethanolamide, an #Oleic acid derivative, may inhibit the release of proinflammatory cytokines induced by SARS-CoV-2, potetially reducing the risk of a patient developing a cytokine storm, which is associated with severe disease and high mortality. [1.2] - Corynebacterium accolens, a benign lipid-requiring species present in nostrils, can inhibit pneumococcal growth when supplemented with human skin surface TAGs thanks to a TAG lipase, LipS1, that hydrolyzes #Triolein into #Oleic acidReferences Notes[ ]
