Diindolylethane {90000737} Record Keys Parent:[ ] Definition:Diindolylethane Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Constitutive androstane receptor , #Diabetes Type 2, #Metabolic associated fatty liver disease] [#3,3′-Diindolylmethane] - CAR plays a critical role in regulating the breakdown, uptake and removal of foreign substances in the liver, including drugs. - CAR plays a role in diabetes, fatty liver disease and small intestine #Ulcerative Colitis - The diindoles, diindolylmethane (DIM) and diindolylethane (DIE) selectively up-regulate bona fide CAR target genes in primary human hepatocytes and mouse liver without causing significant side effects. References Notes[ ]
