Stearate {90000672} Record Keys Parent:[ ] Definition:Stearate Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:Fatty acid Functional Type:Energy Source Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - Numerous animal and plant fats contain stearate, an 18-carbon saturated fatty acid. Stearate is crucial for the growth of different tumors because it alters mitochondrial morphology, rendering #Cancer cells vulnerable to #Oxidative stress and cell death [#Irritable bowel syndrome] - Stearates are also associated with intestinal permeability, which may explain their causal association with IBS. - stearate, a saturated fatty acid, serves as an agonist of Toll-like receptor 4, initiating an inflammatory response and leading to alterations in the gut microbiota. [1.2] [#Irritable bowel syndrome] [#Myristic acid] - elevated concentrations of #Butyryl carnitine and tetradecanedioate are associated with heightened vulnerability to IBS, while increasing levels of stearate (18:0) exhibit a protective effect. - stearate (18:0), #Butyryl carnitine and tetradecanedioate can directly affect IBS independently of other metabolites. References Notes[ ]
