Deazapurine {90000626} Record Keys Parent:[ ] Definition:Deazapurine Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Parkinson’s Disease] - overall increase in fatty acids fermentation to #Lactate and #Ethanol, and lower levels of deazapurine biosynthesis in RBD-FDR, prodromal PD (RBD) and early PD. [#Parkinson’s Disease] - consistent reduction in preQ0 biosynthesis at prodromal PD and early α-synucleinopathy. - PreQ0 is a key intermediate of the biosynthesis of 7-Deazapurine nucleoside. - the abundance of preQ0 biosynthesis seems strongly co-occurring with genus #Faecalibacterium, a butyrate-producing bacteria and an indicator of PD progressionReferences Notes[ ]
