Chitin {90000619} Record Keys Parent:[ ] Definition:Chitin Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - Chitin (β-1,4-poly-N-acetylglucosamine) is a highly abundant natural #Polysaccharide found in arthropods and #Fungi that can initiate type 2 (allergic) immune responses. - The addition of dietary chitin improved metabolic readouts in mice fed a high-fat diet, possibly because activated chief cells produce other digestive enzymes, including lipase. - chitin influences gut microbial composition, ILC2-mediated tissue adaptation and gastrointestinal responses are preserved in germ-free mice. - In the absence of AMCase, sustained chitin intake leads to heightened basal type 2 immunity, reduced adiposity, and resistance to #Obesity.References Notes[ ]
