Citral {90000583} Record Keys Parent:[ ] Definition:Citral Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Metabolic Dysfunction-associated Steatohepatitis] - #Ginger essential oil (GEO) supplementation substantially lower hepatic CYP2E1 protein expression and significantly enhanced the hepatic antioxidant enzyme capacity, including CAT, GRd, and GSH. - GEO alleviates hepatic #Oxidative stress in mice with PL-induced NASH. - GEO alleviated the NASH phenotype and pro-inflammatory cytokines TNF-α, IL-6, and IL-1β. - NASH patients and animal models have exhibited increases in the activation of the NLRP3 inflammasome - GEO exhibited anti-inflammatory activity by reducing NLRP3 inflammasome activation, which may be caused by citral and its isomers.References Notes[ ]
