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DHPPA {90000302}

Record Keys


Parent:[  ]
Definition:
DHPPA
Queue:[  ]

Details


Initialisation date:[  ]
Specification:

3-(3,4-dihydroxyphenyl) propionic acid

Source:
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Meta Information


Structural Type:[  ]
Functional Type:[  ]
Function:[  ]

Notes:


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Shared Reference Notes


  • [1.1] [#Parkinson’s Disease
    - Tyrosine decarboxylase (TyrDC), present in gut microbes, converts #L-Dopa into #Dopamine, which does not cross the blood-brain barrier and accumulates in the gut, causing many side effects such as cardiac arrhythmias and nausea. - levodopa can be metabolized by Clostridium sporogenes to 3-(3,4-dihydroxyphenyl) propionic acid (DHPPA), a metabolite that inhibits muscle contraction in the ileum, reduces intestinal movement, and impairs absorption in the small intestine.

References Notes


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Common References