Uremic toxins {90000208} Record Keys Parent:[ ] Definition:Uremic toxins Queue:[ ] Details Initialisation date:2021-09-21 Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Chronic kidney disease] [1.2] [#Chronic kidney disease] - In CKD patients, the concentrations of microbiota-derived trimethylamine N-oxide (#TMAO), indoxyl #Sulfate and p-cresyl #Sulfate in the blood are increased. Because of poor renal function in CKD patients, these uremic toxins remain in the circulation, promote inflammation, thereby contributing to progressive kidney injury.References Notes[ ]