Cromolyn {90000203} Record Keys Parent:[ ] Definition:Cromolyn Queue:[ ] Details Initialisation date:2021-09-17 Specification: mast cell stabilizerSource: [ ] Meta Information Structural Type:Inorganic Functional Type:[ ] Function:Immun regulator, Anti-inflammatory, Anti-cancer Notes: [ ]Shared Reference Notes [1.1] [#Breast cancer] [#Antibiotic Therapy] - Antibiotic-induced perturbation of the gut microbiota > increases tumor progression in multiple BrCa mouse models > increased number of cells with a stromal signature in tumors > increased abundance of mast cells in the tumor stromal regions. - Re-supplementation of antibiotic-treated mice with #Faecalibaculum rodentium > restored tumor growth to control levels - Mast cell stabilizer, cromolyn > decreases tumor growth only in antibiotic treated animalsReferences Notes[ ]
