Disease ⇒ Dementia ⇒ Dementia with Lewy bodies (DLB) {40000595} Record Keys Type:Disease Parent:Dementia Definition:Dementia with Lewy bodies (DLB) Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Parkinson’s Disease] [#Short Chain Fatty Acid] - short-chain fatty acids-producing genera were decreased in DLB. - #Ruminococcus torques and #Collinsella were increased in DLB, which were not changed in PD. - high #Ruminococcus torques and high #Collinsella, which presumably increase intestinal permeability, as well as low #Bifidobacterium, which are also observed in #Alzheimer’s disease, were predictive of DLB. - #Ruminococcus torques and #Collinsella are also major #Secondary bile acids-producing bacteria, we quantified fecal bile acids and found that the production of #Ursodeoxycholic acid (UDCA) was high in DLB.References Notes[ ]
