Disease ⇒ Diabetic nephropathy {40000457} Record Keys Type:Disease Parent:[ ] Definition:Diabetic nephropathy Details Initialisation date:2021-09-08 Other Terms:[ ] Meta Information MedDra ID:10061835 MedDra Level:pt ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Short Chain Fatty Acid] - SCFA receptors are expressed in the kidneys, and emerging data have demonstrated that intestinal dysbiosis activates the renal renin-angiotensin system, which contributes to the development of DKD. [1.2] [#Probiotic (Bifidobacter and Lactobacilus)] - Probiotics affected lipid metabolism parameters with decreasing triglycerides (TG), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-c) levels in patients with DKD. - Probiotics could also could improve inflammation and oxidative stress by decreasing high-sensitivity C-reactive protein (hs-CRP), plasma malondialdehyde (MDA), total antioxidant capacity (TAC), glutathione (GSH) and nitric oxide (NO).References Notes[ ]
