Disease ⇒ Vulvovaginal candidiasis {40000314} Record Keys Type:Disease Parent:[ ] Definition:Vulvovaginal candidiasis Details Initialisation date:[ ] Other Terms:VVC Meta Information MedDra ID:10047784 MedDra Level:pt ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Vaginal microbiota] [#Candida albicans] - #Lactobacillus spp. produces lactic and other organic acids that contribute to the low pH within the vaginal cavity. - Low pH (< 4.5) inhibits C. albicans yeast-to-hypha transition. - Inflammation furthermore depends on proteases and the toxin #Candidalysin, which not only mediates damage but also directly induces inflammasome-dependent responses of vaginal epithelial cells.References Notes[ ]
