N-methylamino-L-alanine {90000604}

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Definition:
N-methylamino-L-alanine
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Shared Reference Notes

  • [1.1] [#Alzheimer’s disease] 
    - A neurotoxic substance called N-methylamino-L-alanine, generated by an intestinal bacterium called #Cyanobacteria, disrupts the N-methyl-D-aspartate glutamate receptor and contributes to signal dysfunction in AD.
  • [1.2] [#Parkinson’s Disease] 
    - One of the novel OTUs (OTU_171) that we observed to be depleted in PD patients was from the family of #Melainabacteria of the phylum #Cyanobacteria. - Free-living #Cyanobacteria are known to produce a range of neurotoxins, such as Anatoxin and Saxitoxin and the neurotoxin β-N-methylamino-l-alanine (BMAA), which has been linked to neurodegenerative diseases

References Notes

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