N-methylamino-L-alanine {90000604} Record Keys Parent:[ ] Definition:N-methylamino-L-alanine Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Alzheimer’s disease] - A neurotoxic substance called N-methylamino-L-alanine, generated by an intestinal bacterium called #Cyanobacteria, disrupts the N-methyl-D-aspartate glutamate receptor and contributes to signal dysfunction in AD. [1.2] [#Parkinson’s Disease] - One of the novel OTUs (OTU_171) that we observed to be depleted in PD patients was from the family of #Melainabacteria of the phylum #Cyanobacteria. - Free-living #Cyanobacteria are known to produce a range of neurotoxins, such as Anatoxin and Saxitoxin and the neurotoxin β-N-methylamino-l-alanine (BMAA), which has been linked to neurodegenerative diseasesReferences Notes[ ]
