Cytotoxic necrotizing factor 1 {90000498} Record Keys Parent:[ ] Definition:Cytotoxic necrotizing factor 1 Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Colorectal cancer] [#Escherichia coli] - Cytotoxic necrotizing factor 1 (CNF1), a bacterial toxin produced by E. coli, plays a role in the quiescence of disseminated CRC cells. CNF1 blocks cytokinesis, elicits endoreplication and polyploidization, and drives cells into a reversible dormant state.References Notes[ ]