Lipopolysaccharide ⇒ BF-LPS {90000335}

Record Keys


Parent:
Definition:
BF-LPS
Queue:[  ]

Details


Initialisation date:
2022-08-10
Specification:
[  ]
Source:
[  ]

Meta Information


Structural Type:[  ]
Functional Type:[  ]
Function:
Neurotoxic

Notes:


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Shared Reference Notes


  • [1.1] [#Alzheimer’s disease] [#Lipopolysaccharide
    - #Bacteroides fragilis in the human gastrointestinal (GI) tract generates > neurotoxin BF-LPS > BF-LPS leaks out of the GI tract, crosses the blood brain barrier via the circulatory system, and accesses brain compartments > inreases inflammation in brain cells and inhibits neuron-specific neurofilament light (NF-L,) a protein that supports cell integrity > deficiency of NF-L > consequent atrophy of the neuronal cytoskeleton and the disruption of synaptic organization.

References Notes


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