Dimethylglycine {90000298} Record Keys Parent:[ ] Definition:Dimethylglycine Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Diabetes Type 2] - dimethylglycine, #Imidazole propionate, #Tryptophan, #kynurenine and #Indolelactate associated with increased risk of T2D [1.2] - The increased intestinal permeability in C3GnT−/− mice as compared to C3GnT+/+ mice may facilitate the passage of gut-microbe signals/metabolites to the brain, especially those derived from mucus-associated microbes which are in close proximity to the underlying mucosa. - the caecal content of C3GnT−/− mice exhibited altered levels of metabolites linked with #Alzheimer’s disease (AD) and #Depression such as #N-acetyl-lysine derived metabolites, #Acetyl-carnitines, dimethylglycine and #Acetyl-L-Tyrosine.References Notes[ ]
