Tetrahydrobiopterin {90000149} Record Keys Parent:[ ] Definition:Tetrahydrobiopterin Queue:[ ] Details Initialisation date:2021-03-31 Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Cancer] - The enzyme co-factor tetrahydrobiopterin (BH4) is involved in the production of monoamine neurotransmitters, the generation of nitric oxide, and pain. - Administration of BH4 to mice markedly reduces tumour growth and expands the population of intratumoral effector T cells.References Notes[ ]