Diesel Particles {51111204} Record Keys Definition:Diesel Particles Queue:[ ] Details Initialisation date:2022-02-09 Specification: [ ] Meta Information Type:Environment, Socio-economic Host: Mouse Zone: Lung Notes: [ ]Shared Reference Notes [1.1] - DEP-exposure increases lung tumor necrosis factor (TNF)-α, interleukin (IL)-10, Toll-like receptor (TLR)-2, TLR-4, and the nuclear factor kappa B (NF-κB) histologically and by RT-qPCR, as well as Immunoglobulin A (IgA) and Immunoglobulin G (IgG) in the bronchoalveolar lavage fluid (BALF), as quantified by ELISA. We also observed an increase in macrophage infiltration and peroxynitrite, a marker of reactive oxygen species (ROS) + reactive nitrogen species (RNS), immunofluorescence staining in the lungs of DEP-exposed and HF-diet animals, which was further exacerbated by concurrent DEP-exposure and HF-diet consumption.References Notes[ ]