Yogurt consumption {50000137} Record Keys Definition:Yogurt consumption Queue:[ ] Details Initialisation date:2020-08-23 Specification: [ ] LinksInfolink Meta Information Type:Diet Host:[ ] Zone:[ ] Notes: - High levels of yogurt consumption on improving gut barrier function, which separates the intestinal lumen and the underlying lamina propria. In the light of current findings, strengthening the gut barrier could mediate the health benefits of yogurt in adults. - Higher yogurt consumption was associated with lower soluble CD14 concentrations, especially in men. Our findings suggest the strengthening of gut barrier function as a plausible mechanism for the observed inverse associations of yogurt consumption with gastrointestinal diseases and disorders involving other systems. -Plasma sCD14 is a receptor molecule released by macrophages and hepatocytes as part of the innate immune response to lipopolysaccharide and has been used as a marker of gut hyperpermeability.Shared Reference Notes [1.1] - higher abundance of species used as yoghurt starters #Streptococcus thermophilus and sometimes added #Bifidobacterium animalis subsp. lactis in the gut of yoghurt consumers. - Replication in 1103 volunteers from the LifeLines-DEEP cohort confirmed the increase of S. thermophilus among yoghurt consumers. - Using food records collected the day prior to faecal sampling > an increase in these two yoghurt bacteria could be transient. - Metabolomics analysis revealed that B. animalis subsp. lactis > associated with 13 faecal metabolites including a #3-hydroxyoctanoic acid, known to be involved in the regulation of gut inflammation. [1.2] [#Diabetes Type 2, #Obesity] - yogurt intake impacts the hepatic metabolome, notably maintaining the levels of branched chain hydroxy acids (BCHA) which correlate with improved metabolic parametersReferences Notes[ ]