MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Faecalibacterium prausnitzii ⇒ Faecalibacterium {10000130}

Record Keys


Organism:
Faecalibacterium prausnitzii
Parent:

Details


Authoring date:
2020-09-06

Links


Meta Information


Taxonomy:
Species
Domain:
Bacteria
Zone:
Gut Lumen
Enzyme:[  ]
Function:
Anti-inflammatory

Notes


- F. prausnitziiis the largest producer of butyrate and the largest consumer of acetate and is the most important species inhabiting the intestine. Its depletion along with the reduction of Bifidobacterium (which is more reduced in patients with kidney stones) leads to a reduction in the intestinal butyrate levels, which thence leads to a functional instability in the gastrointestinal tract and urothelium thereby resulting in an inflammatory pattern. (1)

-These bacteria, which are often diminished in patients with Crohn's disease, appear to exert many of their protective effects through the release of a fatty acid called butyrate.

Common References