MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Bifidobacterium {10000120}

Record Keys


Organism:
Bifidobacterium
Class:[  ]

Details


Initialisation date:
2020-09-06

Links


Meta Information


Taxonomy:
Genus
Domain:
Bacteria
Zone:[  ]
Enzyme:[  ]
Function:
Anti-inflammatory , Anti-cancer

Notes


Bifidobacter

Shared Notes


  • [1.136
    - Bifidobacterium can resist the antimicrobial activity of bile salts.
  • [1.137
    - The reduction of Bifidobacterium also results in reduced levels of short-chain fatty acids (SCFAs), common in ASD children.
  • - Bifidobacterium can produce GABA
  • [1.138
    - Bifidobacterium is associated with antitumor effects, and oral administration of Bifidobacterium alone improved tumor control to the same degree as PD-L1 antibody therapy while combination treatment nearly abolished tumor growth in mice.
  • [1.139
    - High levels of plant dietary fibers in the gut resulted in proliferation of Bifidobacterium with anti-inflammatory and anti-tumor effects
  • [1.140
    - Bifidobacterium species decrease cancer cell proliferation via the inhibition of growth factor signaling as well as inducing mitochondrial-mediated apoptosis.
    - Bifidobacterium species reduce the adverse effects of chemo/immuno/radiation therapy by inhibiting proinflammatory cytokines.
  • [1.141
    - Bifidobacterium appears to be the most consistently supported by the literature genus containing microbes potentially protective against T2D
  • [1.142
    - Bifidobacterium generate GABA.
  • [1.143
    - HSD increased the abundance of Bifidobacterium and caused increased gut permeability leading to intratumor localization of Bifidobacterium, which enhanced NK cell functions and tumor regression.
    - Intratumoral injections of Bifidobacterium activated NK cells, which inhibited tumor growth.
  • [1.144
    - Bifidobacterium breve have a positive correlation with acetic acid levels and intestinal epithelium expression of tight junction-related genes.

Common References