MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

IL-17A {60000086}

Record Keys


Biotic:
IL-17A
Parent:[  ]
Queue:[  ]

Details


Authoring date:
2020-10-04
Specification:
[  ]
Source:
[  ]

Meta Information


Structural Type:[  ]
Functional Type:[  ]
Function:
Pro-inflammatory

Notes


[  ]

Shared Notes


  • [1.1
    - IL-17A is expressed in mucosal cells and contributes to intestinal homeostasis but might promote inflammation in excess.
    - IL-17A is mainly produced by Th17 cells. It can also be produced by γδ T cells, natural killer (NK) T cells, macrophages, neutrophils, and eosinophils, but their regulation of IL-17A expression is different.
    - IL-17 molecules from the gut can influence autoimmune diseases in the central nervous system by regulating the gut microbiota rather than directly triggering brain inflammation

Common References