5-aminovaleric acid {60000061} Record Keys Parent:[ ] Definition:5-aminovaleric acid Queue:[ ] Details Initialisation date:2020-09-22 Specification: 5AVSource: [ ] Meta Information Structural Type:[ ] Functional Type:Neurotransmitter Function:Neurodevelopment Notes: - 5-aminovaleric acid (5AV) was significantly lower in oASD mice (Figure 4G). 5AV is a weak GABAA receptor agonist and is significantly lower in individuals with ASD (1)Shared Reference Notes [1.1] [#Metabolic associated fatty liver disease] - Fatty Liver > increased N, N, N-trimethyl-5-aminovaleric acid [1.2] - certain bacteria-related metabolites, such as trimethylamine-N-oxide (#TMAO), 5-aminovaleric acid (5-AVA), #5-AVA Betaine (5-AVAB), #Imidazolepropionic acid, and #Hippuric acid have been reported to promote early-life axonogenesis both in vitro and in vivo.References Notes [1.3]