MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Taurine {60000060}

Record Keys


Biotic:
Taurine
Class:[  ]
Queue:[  ]

Details


Initialisation date:
2020-09-22
Specification:

- 2-aminoethanesulfonic acid
- It is a major constituent of bile
- Reduce the secretion of apolipoprotein B100 and lipids in HepG2 cells

Source:

Fish, Meat, Breast milk, Raw diets, Energy drinks

Meta Information


Structural Type:[  ]
Functional Type:
Neurotransmitter
Function:
Anti-oxidant, Anti-atherosclerosis, Neurodevelopment

Notes


- Lower levels of another weak GABAA agonist (and a potent glycine receptor agonist), namely taurine, are found in a subset of individuals with ASD (1)

Shared Notes


  • [1.2
    - Prior gut infection increases the microbiota’s resistance to subsequent infection.
    - Sulfide sequestration unleashes endogenous respirers in the gut microbiota.
    - After infection by K. pneumoniae, the level of the molecule taurine rises in the gut.
    - Taurine is produced from the metabolism of bile acids.
    . After infection, resident bacteria that can use taurine become more common in the gut.
  • [1.3
    - Diet rich in high saturated fats promotes chronic inflammation.
    - One explanation is that the amino acid taurine, present in saturated fats, linked to bile acids, seems to increase substrate availability for sulfur-reducing bacteria like Bilophila Wadsworthia, highly prevalent in the dysbiotic microbiota of IBD patients.

Common References