Oleocanthal {90000486} Record Keys Parent:[ ] Definition:Oleocanthal Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Alzheimer’s disease] [#Olive] - In several rodent studies, EVOO, especially the EVOO #Secoiridoid oleocanthal, aided the prevention and halted the progression of AD [#Alzheimer’s disease] [#Olive] - oleocanthal-rich EVOO given to TgSwDI mice at an advanced stage of AD resulted in significantly reduced NLRP3 inflammasome activation and increased Aβ clearance by stimulating autophagy through the AMPK− Unc-51-like kinase 1 (ULK1) pathway.References Notes[ ]