Trehalose {90000384} Record Keys Parent:[ ] Definition:Trehalose Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:Neuroprotector Notes: [ ]Shared Reference Notes [1.1] [#Parkinson’s Disease] - The disaccharide trehalose has garnered significant interest as a therapeutic molecule in PD and other neurodegenerative diseases- . This is likely due to its activities on autophagocytic pathways which limit the accumulation of pathogenic alpha-synuclein and other protein aggregates. - two-fold increase was observed in the PD metagenome of the trehalose degradation pathway - increased metabolism of trehalose by bacteria, a potential outcome of which is reduced availability of trehalose for the host.References Notes[ ]
