Delta-valerobetaine {90000257} Record Keys Parent:[ ] Definition:Delta-valerobetaine Queue:[ ] Details Initialisation date:2022-02-07 Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - In 214 humans, they found the average blood levels of delta-valerobetaine was 40 percent higher for people with a BMI greater than 30 compared to those with lower BMIs. - delta-valerobetaine contributes to #Obesity and hepatic steatosis by modulating mitochondrial fatty acid oxidation and increasing lipid storage in the adipose tissue and liver. [1.2] - delta-valerobetaine production by the gut microbiome reduces cellular carnitine and mitochondrial long-chain acyl-coenzyme A (acyl-CoA); consequently, this obesogenic metabolite prevents mitochondrial fatty acid oxidation and leads to diet-dependent #Obesity.References Notes[ ]
