Trichloroethylene {90000150}
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| Definition: | Trichloroethylene |
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| Initialisation date: | 2021-04-11 |
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TCE | |
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Shared Reference Notes
- [1.1] [#Parkinson’s Disease]
- Trichloroethylene (TCE) is an environmental contaminant and Parkinson’s risk factor. - Chronic TCE treatment in rats caused dopaminergic neurodegeneration. - TCE exposure elevated LRRK2 kinase activity in the nigrostriatal tract and causes dopaminergic pathology, endolysosomal dysfunction, protein accumulation. - [1.2] [#Alzheimer’s disease]
References Notes
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