test Exposure to Glyphosate | Factor | MetaBiom
MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Exposure to Glyphosate {51111164}

Record Keys


Factor:
Exposure to Glyphosate
Queue:[  ]

Details


Authoring date:
2020-12-07
Specification:

Roundup 3

Meta Information


Type:
Antibacterial, Environment
Host:
Human
Mouse
Zone:[  ]

Notes


[  ]

Shared Notes


  • [1.1
    - High-dose glyphosate exposure causes higher levels of pro-inflammatory cytokines including IL-1β, IL-6 and TNF-α in addition to increased transcription of mitogen-activated protein (MAP) kinase and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) within the small intestine.
    - Subspecies of the Rothia genus have been identified as playing a critical role in the degradation of gluten within the mouth and upper gastrointestinal tract.
    - Gluten proteins are difficult to digest by mammalian proteolytic enzymes and recent studies have highlighted microorganism derived enzymes which aid in breaking down these proteins.
    - Rothia spp., contain not only the enzymes necessary for protein degradation but also have enzymes that target the immunogenic epitopes that play a crucial role in celiac disease.
    - Exposure to Roundup 3Plus® during pregnancy significantly increased the abundance of Turicibacter spp which, in combination with Clostridiaceae, plays a critical role in the modulation of gut-derived serotonin

Common References