test Mediterranean diet | Factor | MetaBiom
MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Mediterranean diet {51111163}

Record Keys


Factor:
Mediterranean diet
Queue:[  ]

Details


Authoring date:
2020-12-04
Specification:

MedD

Meta Information


Type:
Diet
Host:
Human
Zone:[  ]

Notes


[  ]

Shared Notes


  • [1.1
    - Reductions in branched-chain fatty acids (BCFAs), such as valerate, isovalerate, isobutyrate and 2-methylbutyrate in the faeces.
    - Increased levels of the fibre-degrading Faecalibacterium prausnitzii and of genes for microbial carbohydrate degradation linked to butyrate metabolism.
    - The dietary changes in the MedD group led to increased urinary urolithins, faecal bile acid degradation and insulin sensitivity that co-varied with specific microbial taxa.
    - Higher abundance of different taxa that were positively linked to markers of lower frailty and better cognitive function and negatively associated with inflammatory markers such as C-reactive protein and interleukin-17.
    - Increased abundance of butyrate-producing bacteria Faecalibacterium prausnitzii and Roseburia.
    - Lower abundance of the potentially proinflammatory Ruminococcus gnavus and R. torques
    - Increased urinary levels of urolithin glucuronides produced by urolithin-producing gut bacteria.
    - R. gnavus is a proinflammatory species due to secretion of a polysaccharide that induces tumour necrosis factor alpha in
    dendritic cells.

Common References