MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Sugar intake {51111159}

Record Keys


Factor:
Sugar intake
Queue:[  ]

Details


Authoring date:
2020-11-02
Specification:
[  ]

Meta Information


Type:
Diet, Habit
Host:
Mouse
Zone:
Faeces

Notes


- The abundance of the mucus-degrading bacteria Akkermansia muciniphila and Bacteroides fragilis was increased.
- Bacteria-derived mucolytic enzymes were enriched leading to erosion of the colonic mucus layer of sugar-fed mice.
- Sugar-induced exacerbation of colitis was not observed when mice were treated with antibiotics or maintained in a germ-free environment, suggesting that altered microbiota played a critical role in sugar-induced colitis pathogenesis. .(1)