MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Oral administration of Abiraterone acetate {50000148}

Record Keys


Factor:
Oral administration of Abiraterone acetate
Queue:[  ]

Details


Authoring date:
2020-09-30
Specification:
[  ]

Meta Information


Type:
Drug
Host:
Human
Zone:[  ]

Notes


- Androgen deprivation (Abiraterone acetate ) therapy depletes androgen-utilizing Corynebacterium spp. in prostate cancer patients and that oral AA further enriches for the health-associated commensal, Akkermansia muciniphila. Functional inferencing elucidates a coinciding increase in bacterial biosynthesis of vitamin K2 (an inhibitor of androgen dependent and independent tumor growth) (1)