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Microbiome & Chronic Diseases

Evidence Based Medicine
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Fasting {50000141}

Record Keys


Factor:
Fasting
Queue:[  ]

Details


Initialisation date:
2020-09-25
Specification:

Intermittent Fasting

Meta Information


Type:
Diet, Habit
Host:
Human
Zone:
Gut Lumen

Notes


- Causes rapid expansion of a particular bacteria Akkermansia muciniphila. (1)

Shared Notes


  • [1.1
    - A 5-day fast followed by a modified Dietary Approach to Stop Hypertension diet reduces systolic blood pressure, need for antihypertensive medications, body-mass index at three months post intervention compared to a modified Dietary Approach to Stop Hypertension diet alone.
    - Fasting alters > gut microbiome > impacting bacterial taxa and gene modules associated with short-chain fatty acid production.
  • [1.2
    - Calorie restriction (CR) without malnutrition remains the most robust intervention to date for cancer prevention in rodents and monkeys, and, in humans, it promotes anticarcinogenic adaptations such as decreased production of growth factors, inflammatory cytokines, and anabolic hormones as well as decreased oxidative stress and free-radical–induced DNA damage.
  • [1.3
    'Ä&%$)((/

Common References