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Crohn's disease {40000108}

Record Keys


Definition:
Crohn's disease
Class:[  ]

Details


Other Terms:
Regional Enteritis, Granulomatous Ileitis, Granulomatous Ileocolitis
Initialisation date:
2019-05-15

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Meta Information


ICD:[  ]
Category:
Gastroenterology
MedDra ID:
10011401
MedDra Level:
pt

Notes


- Fucose (type of Sugar) > 1,2-propanediol > AIEC (type of E. Coli) > Propionate > Inflamation of Gut wall
- Reducing of Fucose ( type of Sugar) may ameliorate the Inflammation of Crohn's disease.

- In Crohn’s disease, there is increased abundance for degradation of glycosaminoglycans and B-vitamin biosynthesis.
- There is a decrease in abundance of methanogenesis , antimicrobial peptide response , and phosphatidylethanolamine biosynthesis. (1)

- Prior use of antibiotics is associated with a nearly 2 times increased risk of developing IBD compared with no prior use. (2)

- Patients with Crohn's disease has significantly higher levels of the fungus Candida tropicalis and the bacteria Escherichia coli and Serratia marcescens than their healthy relatives.
-These three organisms interacted in a strategic way to form robust, pathogenic biofilms capable of driving intestinal inflammation (4)

- Electron microscopy showed that E. coli fuse to the C. tropicalis growths. Meanwhile S. marcescens make protein strings that somehow stabilize the biofilm. (5)

- Patients with Crohn NULLs disease showed significantly higher levels of the fungus Candida tropicalis and the bacteria Escherichia coli and Serratia marcescens than their healthy relatives. Further in vitro studies showed that these three organisms interacted "in a strategic way" to form robust, pathogenic biofilms capable of driving intestinal inflammation. (6)

- Patients with Crohn's disease showed significantly higher levels of the fungus Candida tropicalis and the bacteria Escherichia coli and Serratia marcescens than their healthy relatives. Further in vitro studies showed that these three organisms interacted "in a strategic way" to form robust, pathogenic biofilms capable of driving intestinal inflammation. (13)


Shared Notes


  • [1.41
    - The microbiome in the inflamed and proximal noninflamed ileal mucosa do not differ according to alpha diversity or beta diversity.
  • [1.55
    - Significantly lower abundances of Coprococcus in CD, Dialister in MS, and Roseburia in RA.
  • [1.25
    - Adherent-invasive E. coli (AIEC) are enriched in the intestinal microbiota of patients with Crohn’s disease (CD) and promote intestinal inflammation.
  • [1.56
    - Comprehensive overview of functional dysbiosis in the gut microbiome during IBD activity showed increases in facultative anaerobes, such as E. coli which correlates with inflammation status, and decreases in obligate anaerobes, such as Faecalibacterium prausnitzii and Roseburia hominis
    -The results of the present study confirmed decreases in the abundance of Firmicutes and Bacteroidetes, increases in Enterobacteriaceae, Pasteurellaceae, and Veillonellaceae and the presence of Fusobacterium in stool samples of CD patients.
    - Butyrate-producing bacteria are depleted in IBD patients, and probiotic treatment with these bacteria has therapeutic potential.
    - A higher proportion of Lachnospiraceae in donor stool was associated with a higher success rate of FMT [85], and recipients that responded to FMT exhibited increases in butyrate-producing Lachnospiraceae and Ruminococcaceae.
    - The reduced SCFA levels in patients with IBD result from lower abundance of SCFA-producing bacteria, especially those of the phylum Firmicutes.
  • [1.24
    - Debaryomyces hansenii preferentially localized to and was abundant within incompletely healed intestinal wounds of mice and inflamed mucosal tissues of CD human subjects.
    - D. hansenii cultures from injured mice and inflamed CD tissues impaired colonic healing when introduced into injured conventionally raised or gnotobiotic mice.
    - Mechanistically, D. hansenii impaired mucosal healing through the myeloid cell–specific type 1 interferon–CCL5 axis.
  • [1.57
    - Long-term intake of fibers from fruit > protective against the development of CD, but not of UC
  • [1.58
    - The oral microbe Streptococcus salivarius was found to be enriched and of concordant strains in the gut and oral microbiome of Crohn’s disease subjects. This was more likely in CD subjects with higher Crohn’s Disease Activity Index and active disease status (Diarrhoea/abdominal pain/blood-in-stool/fever and fatigue).
  • - Gut species found to be significantly depleted in CD compared to control include: Faecalibacterium prausnitzii , Roseburia inulinivorans and Alistipes senegalensis.
    - While Clostridium nexile and Ruminococcus gnavuswere found to be enriched.
  • - Microbial arginine and isoprene pathways were found at a higher relative abundance level in gut microbiome of Crohn’s disease.
  • [1.59
    - Bacteroides vulgatus is both directly associated with Th17 immunity and has a higher abundance in active CD relative to non-IBD controls.
    - The increase of Bacteroides vulgatus abundance in active CD can induce more Th17 cells that in turn might worsen IBD inflammation.
  • [1.60
    - Adherent-invasive E. coli (AIEC), > prevalent in up to half the individuals with Crohn’s Disease (CD)
    - Among the genes related to AIEC pathogenicity, fim has the potential to generate an inflammatory reaction from the intestinal epithelial cells and macrophages, as it interacts with TLR4, inducing the production of inflammatory cytokines independently of LPS.
  • [1.61
    - Stress-exposed mice > develop ileal dysbiosis, dominated by the expansion of Enterobacteriaceae.
    - Stress-induced glucocorticoids promote > apoptosis of CD45+CD90+ cells that normally produce IL-22, a cytokine that is essential for the maintenance of ileal mucosal barrier integrity.
    - Blockade of glucocorticoid signaling or administration of recombinant IL-22 > restores mucosal immunity, prevents ileal dysbiosis.
  • [1.63
    - triclosan (TCS), an antimicrobial agent found in thousands of consumer products > exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models.
    - intestinal commensal microbes > microbial β-glucuronidase (GUS) enzymes > mediate metabolic activation of triclosan in the colon > gut toxicology.
  • [1.64
    - C tropicalis > induces dysbiosis that involves changes in the presence of mucin-degrading bacteria Akkermansia muciniphila and Ruminococcus gnavus > leading to altered tight junction protein expression with increased intestinal permeability > followed by induction of robust Th1/Th17 responses > lead to an accelerated proinflammatory phenotype in experimental colitic mice.
  • [1.65
    - Two commonly used emulsifiers, carboxymethylcellulose and polysorbate-80 > induce inflammation and metabolic changes, mediated by gut microbes.
  • [1.66
    - a portion of the microbiota-driven sIgA response is induced by and directed towards intestinal fungi. Analysis of the human gut mycobiota bound by sIgA revealed a preference for hyphae, a fungal morphotype associated with virulence. Candida albicans was a potent inducer of IgA class-switch recombination among plasma cells, via an interaction dependent on intestinal phagocytes and hyphal programming. Characterization of sIgA affinity and polyreactivity showed that hyphae-associated virulence factors were bound by these antibodies and that sIgA influenced C. albicans morphotypes in the murine gut.
  • [1.67
    - adherent-invasive Escherichia coli (AIEC), and Salmonella enterica serovar Typhimurium > induce inflammation (through elevated T helper (TH) 1 and TH17 immune responses) in IBD animal model > fibrosis development.
    - in patients with Crohn’s disease, AIEC strains > ileal mucosa > trigger the initiation or perpetuation of the inflammatory disease.
  • [1.68
    - Probiotic treatment with butyrate-producing bacteria has therapeutic potential since these bacteria are depleted in IBD patients and butyrate has beneficial effects on epithelial barrier function and overall gut health.
  • [1.69
    - the aggregated relative abundance of Klebsiella species was significantly higher in patients with Crohn NULLs disease and primary sclerosing cholangitis when compared with healthy controls. In addition, several genes that have been previously reported to be increased in the faecal microbiomes of patients with inflammatory bowel diseases -genes that include hemolysin-coregulated protein and enzymes involved in fructose-, galactitol-, mannose-, and long-chain fatty acid-related uptake and metabolic pathways- were enriched in most faecal samples of the patients with inflammatory disease who carried Klebsiella species.
    - The common skin resident fungus Malassezia restricta, is also linked to the presence of an IBD-associated polymorphism in the gene for CARD9, a signaling adaptor important for anti-fungal defense. M. restricta elicits innate inflammatory responses largely through CARD9 and is recognized by Crohn NULLs disease patient anti-fungal antibodies. This yeast elicits strong inflammatory cytokine production from innate cells harboring the IBD-linked polymorphism in CARD9 and exacerbates colitis via CARD9 in mouse models of disease.
  • [1.70
    - Notably, taxonomic perturbations during dysbiosis mirrored those previously observed cross-sectionally in IBD6, such as the depletion of obligate anaerobes including Faecalibacterium prausnitzii and Roseburia hominis in CD and the enrichment of facultative anaerobes such as E. coli.
    - depletion of obligate anaerobes including Faecalibacterium prausnitzii and Roseburia hominis in CD and the enrichment of facultative anaerobes such as E. coli.
    - The reduction in butyrate in particular is consistent with the previously observed depletion of butyrate producers such as F. prausnitzii and R. hominis, which was also observed here.- depletion of obligate anaerobes including Faecalibacterium prausnitzii and Roseburia hominis in CD and the enrichment of facultative anaerobes such as E. coli
    - The reduction in butyrate in particular is consistent with the previously observed depletion of butyrate producers such as F. prausnitzii and R. hominis, which was also observed here.


[Overlap other Diseases]

DiseaseOverlapCommon increased OrganismCommon decreased Organism
Crohn's disease 1.0000 129 (1.00) : Acidaminococcus | Acinetobacter | Actinobacillus | Actinomyces | Aeromonas | Alicyclobacillus | Alternaria brassicicola | Anaerostipes | Anaerotruncus | Anaerovorax | Anelloviridae | Aspergillus clavatus | Bacteroides caccae | Bacteroides clarus | Bacteroides fragilis | Bacteroides ovatus | Bacteroides ureolyticus | Bacteroides vulgatus | Bacteroides-Prevotella group | Barnesiellaceae | Bifidobacterium | Blautia | Burkholderia | Campylobacter gracilis | Candida | Candida albicans | Candida glabrata | Candida tropicalis | Capnocytophaga | Caulobacteriaceae | Cetobacterium | Citrobacter | Clostridioides difficile | Clostridium | Clostridium boltae | Clostridium butyricum | Clostridium cluster XIVa | Clostridium lactatifermentans | Clostridium leptum | Clostridium ramosum | Collinsella | Coprococcus | Cortinariaceae | Cryptococcus neoformans | Cystofilobasidiaceae | Debaryomyces hansenii | Dioszegia | Dipodascus | Eggerthella | Eikenella | Enterobacteriaceae | Enterobacteriaceae bacterium | Enterococcus | Entero 165 (1.00) : Adlercreutzia | Akkermansia | Akkermansia muciniphila | Alistipes | Alistipes indistinctus | Alistipes putredinis | Anaerofustis | Anaerostipes | Anaerostipes hadrus | Anaerotruncus | Asaccharobacter | Bacillus | Bacillus coagulans | Bacteriodes uniformis | Bacteroides | Bacteroides eggerthii | Bacteroides fragilis | Bacteroides massiliensis | Bacteroides pectinophilus | Bacteroides vulgatus | Bacteroides xylanolyticus | Bacteroidetes | Barnesiellaceae | Bifidobacterium | Bifidobacterium adolescentis | Bifidobacterium catenulatum | Bifidobacterium longum | Bilophila | Blautia | Blautia coccoides | Blautia faecis | Brachyspira | Butyricicoccus pullicaecorum | Butyricimonas | Cellulosilyticum | Christensenella | Christensenella minuta | Christensenellaceae | Citrobacter | Cloacibacillus | Clostridiales | Clostridium | Clostridium asparagiform | Clostridium celatum | Clostridium cellulovorans | Clostridium cluster IV | Clostridium coccoides group | Clostridium disporicum | Clostridium lactafifermentans | Clostri
Ulcerative Colitis 0.1959 36 (0.13) : Actinomyces | Anaerostipes | Anelloviridae | Bacteroides fragilis | Bacteroides vulgatus | Bifidobacterium | Blautia | Burkholderia | Citrobacter | Clostridioides difficile | Clostridium | Clostridium ramosum | Dipodascus | Eggerthella | Enterobacteriaceae | Enterococcus | Entyloma | Escherichia coli | Faecalicoccus | Flavonifractor plautii | Fusobacterium nucleatum | Gardnerella vaginalis | Haemophilus | Lactobacillales | Lactobacillus | Prevotella | Rothia | Ruminococcus | Ruminococcus gnavus | Ruminococcus torques | Shigella | Staphylococcus aureus | Streptococcus | Turicibacter | Tyzzerella | Veillonella 64 (0.26) : Akkermansia muciniphila | Alistipes | Anaerostipes hadrus | Bacteroides | Bacteroides fragilis | Bacteroides massiliensis | Bifidobacterium | Bilophila | Blautia | Blautia coccoides | Brachyspira | Butyricicoccus pullicaecorum | Butyricimonas | Christensenella | Christensenellaceae | Cloacibacillus | Clostridium cellulovorans | Clostridium cluster IV | Clostridium coccoides group | Clostridium leptum | Collinsella aerofaciens | Coprococcus | Coriobacteriaceae | Defluviitalea | Desulfovibrio | Dialister | Enterococcus | Eubacterium | Eubacterium rectale | Faecalibacterium prausnitzii | Fusobacteria | Gemmiger | Gemmiger formicilis | Haemophilus | Hanseniaspora | Helicobacter | Hypsizygus | Lachnobacterium | Lachnospira | Lachnospiraceae | Lactobacillus | Leucosporidium | Methanobrevibacter | Mogibacterium | Naganishia | Neisseria | Odoribacter | Oscillospira | Oxalobacter | Peptococcus | Phascolarctobacterium | Prevotella | Pseudomonas | Rikenellaceae | Roseburia | Roseburia hominis | Ruminococcus bromii | Rum
Colorectal cancer 0.1101 30 (0.05) : Acinetobacter | Actinobacillus | Actinomyces | Anaerotruncus | Bacteroides fragilis | Bifidobacterium | Burkholderia | Clostridioides difficile | Clostridium ramosum | Collinsella | Eikenella | Enterobacteriaceae | Enterococcus | Escherichia | Escherichia coli | Fusobacterium | Fusobacterium nucleatum | Klebsiella | Lactobacillus | Parvimonas micra | Peptoniphilus | Peptostreptococcus | Peptostreptococcus anaerobius | Prevotella | Pseudomonas | Ruminococcus | Stenotrophomonas | Streptococcus | Streptococcus anginosus | Turicibacter 55 (0.17) : Akkermansia | Alistipes | Alistipes putredinis | Anaerostipes | Anaerotruncus | Bacillus | Bacteriodes uniformis | Bacteroides | Bacteroides fragilis | Bifidobacterium | Bifidobacterium catenulatum | Blautia | Blautia coccoides | Christensenella | Clostridiales | Clostridium leptum | Collinsella | Collinsella aerofaciens | Coprococcus | Desulfovibrio | Dialister | Dialister invisus | Dorea | Eubacterium | Eubacterium rectale | Eubacterium ventriosum | Faecalibacterium | Faecalibacterium prausnitzii | Haemophilus | Janthinobacterium | Klebsiella | Lachnospira | Lachnospiraceae | Lactobacillus | Megasphaera | Methanobrevibacter | Mitsuokella | Mogibacterium | Neisseria | Oscillibacter | Parabacteroides | Paraprevotella | Phascolarctobacterium | Prevotella | Pseudoflavonifractor | Pseudomonas | Rikenellaceae | Roseburia | Ruminococcaceae | Ruminococcus | Ruminococcus albus | Sphingobacterium | Stenotrophomonas | Streptococcus | Streptococcus salivarius
Irritable bowel syndrome 0.0954 28 (0.08) : Acinetobacter | Actinomyces | Aeromonas | Anaerovorax | Bifidobacterium | Blautia | Candida tropicalis | Citrobacter | Clostridioides difficile | Clostridium leptum | Collinsella | Enterobacteriaceae | Enterococcus | Escherichia | Escherichia coli | Faecalibacterium prausnitzii | Flavonifractor plautii | Haemophilus parainfluenzae | Klebsiella | Lactobacillales | Lactobacillus | Odoribacter | Prevotella | Ruminococcus gnavus | Staphylococcus | Streptococcus | Streptococcus intermedius | Veillonella 33 (0.11) : Alistipes | Anaerostipes | Bacteriodes uniformis | Bacteroides | Bacteroides fragilis | Bacteroides vulgatus | Bifidobacterium | Bifidobacterium catenulatum | Blautia | Blautia coccoides | Christensenellaceae | Citrobacter | Clostridium lituseburense | Collinsella aerofaciens | Coprococcus | Coprococcus eutactus | Desulfovibrio | Dorea | Eubacterium | Faecalibacterium | Gemella | Haemophilus | Lachnospira | Lachnospiraceae | Lactobacillus | Neisseria | Odoribacter | Oscillibacter | Parabacteroides | Roseburia | Ruminococcaceae | Streptococcus | Vivictivallis
Clostridium difficile infection 0.0953 16 (0.07) : Citrobacter | Clostridioides difficile | Clostridium | Eggerthella | Enterobacteriaceae | Enterococcus | Escherichia coli | Klebsiella | Lactobacillus | Morganella | Proteus | Ruminococcus | Shigella | Staphylococcus | Turicibacter | Veillonella 25 (0.12) : Akkermansia | Alistipes | Anaerostipes | Anaerotruncus | Bacteroides | Barnesiellaceae | Bifidobacterium | Butyricimonas | Christensenellaceae | Collinsella | Coprococcus | Coriobacteriaceae | Dialister | Faecalibacterium | Faecalibacterium prausnitzii | Haemophilus | Lachnospira | Odoribacter | Oscillospira | Paraprevotella | Phascolarctobacterium | Prevotella | Rikenellaceae | Ruminococcaceae | Subdoligranulum
HIV infection 0.0933 27 (0.07) : Acinetobacter | Anaerotruncus | Candida | Candida albicans | Candida tropicalis | Capnocytophaga | Citrobacter | Enterobacteriaceae | Escherichia | Finegoldia | Fusobacterium | Haemophilus | Haemophilus parainfluenzae | Klebsiella | Lactobacillus | Malassezia restricta | Pelomonas | Peptoniphilus | Peptostreptococcus | Prevotella | Prevotella melaninogenica | Proteobacteria | Ruminococcus | Shigella | Stenotrophomonas | Streptococcus | Veillonella 37 (0.12) : Akkermansia | Alistipes | Bacteroides | Bacteroidetes | Barnesiellaceae | Bifidobacterium | Bilophila | Blautia | Brachyspira | Christensenellaceae | Clostridium | Collinsella | Coprococcus | Dialister | Dorea | Eubacterium | Faecalibacterium | Haemophilus | Helicobacter | Lachnobacterium | Lachnospira | Lachnospiraceae | Neisseria | Odoribacter | Oscillospira | Oxalobacter | Parabacteroides | Prevotella | Pseudomonas | Rikenellaceae | Roseburia | Ruminococcaceae | Ruminococcus | Streptococcus | Streptococcus mitis | Turicibacter | Vivictivallis
Obesity 0.0909 27 (0.05) : Bacteroides fragilis | Bacteroides vulgatus | Bifidobacterium | Blautia | Clostridium | Clostridium cluster XIVa | Collinsella | Coprococcus | Escherichia | Faecalibacterium prausnitzii | Fusobacterium | Fusobacterium nucleatum | Haemophilus | Lactobacillus | Peptoniphilus | Prevotella | Prevotella melaninogenica | Proteobacteria | Pseudomonas | Ruminococcus torques | Staphylococcus | Staphylococcus aureus | Stenotrophomonas | Streptococcus anginosus | Streptococcus intermedius | Streptococcus mutans | Veillonella parvula 48 (0.13) : Akkermansia | Akkermansia muciniphila | Alistipes | Anaerostipes | Anaerostipes hadrus | Anaerotruncus | Bacteriodes uniformis | Bacteroides | Bacteroides pectinophilus | Bacteroides vulgatus | Bacteroidetes | Bifidobacterium | Bifidobacterium adolescentis | Bifidobacterium longum | Blautia | Butyricimonas | Christensenellaceae | Clostridium cluster IV | Clostridium disporicum | Clostridium leptum | Coprococcus | Coriobacteriaceae | Dialister | Eubacterium | Eubacterium hallii | Faecalibacterium | Faecalibacterium prausnitzii | Holdemania | Klebsiella | Lachnospira | Lachnospiraceae | Lactobacillus | Megasphaera | Methanobrevibacter | Odoribacter | Oscillibacter | Oscillospira | Paludibacter | Parabacteroides | Paraprevotella | Phascolarctobacterium | Prevotella | Roseburia | Ruminiclostridium | Ruminococcaceae | Ruminococcus | Ruminococcus flavefaciens | Streptococcus
Type 2 diabetes 0.0907 36 (0.09) : Acidaminococcus | Acinetobacter | Actinomyces | Bacteroides caccae | Bifidobacterium | Burkholderia | Campylobacter gracilis | Clostridium boltae | Clostridium ramosum | Eggerthella | Enterococcus | Escherichia | Escherichia coli | Finegoldia | Fusobacterium | Fusobacterium nucleatum | Haemophilus | Klebsiella | Lachnospiraceae | Lactobacillus | Parabacteroides distasonis | Parvimonas micra | Peptostreptococcus | Prevotella | Pseudomonas | Ruminococcus gnavus | Shigella | Sphingomonas | Staphylococcus | Stenotrophomonas | Streptococcus | Streptococcus anginosus | Streptococcus intermedius | Streptococcus mutans | Streptococcus salivarius | Veillonella parvula 38 (0.10) : Adlercreutzia | Akkermansia | Akkermansia muciniphila | Anaerostipes | Bacteriodes uniformis | Bacteroides vulgatus | Bifidobacterium | Bifidobacterium adolescentis | Bilophila | Blautia coccoides | Butyricimonas | Clostridium leptum | Collinsella | Coprococcus | Dialister invisus | Dorea | Erysipelotrichaceae | Eubacterium | Eubacterium rectale | Faecalibacterium | Faecalibacterium prausnitzii | Haemophilus | Klebsiella | Lachnobacterium | Lachnospira | Lachnospiraceae | Neisseria | Odoribacter | Oscillospira | Parabacteroides | Paraprevotella | Phascolarctobacterium | Prevotella | Pseudomonas | Roseburia hominis | Roseburia intestinalis | Roseburia inulinivorans | Streptococcus
Autism 0.0885 27 (0.05) : Bacteroides fragilis | Bacteroides vulgatus | Bifidobacterium | Burkholderia | Candida | Clostridioides difficile | Clostridium | Clostridium boltae | Clostridium ramosum | Collinsella | Enterobacteriaceae | Enterococcus | Faecalibacterium prausnitzii | Flavonifractor plautii | Haemophilus | Lachnobacterium | Lachnospiraceae | Lactobacillus | Odoribacter | Parabacteroides distasonis | Pseudomonas | Rothia | Ruminococcus | Ruminococcus gnavus | Ruminococcus torques | Shigella | Streptococcus 51 (0.13) : Adlercreutzia | Akkermansia | Alistipes | Anaerostipes | Anaerotruncus | Bacteriodes uniformis | Bacteroides | Bacteroides fragilis | Bacteroides massiliensis | Bacteroides vulgatus | Bacteroidetes | Bifidobacterium | Bifidobacterium adolescentis | Bifidobacterium longum | Bilophila | Blautia | Butyricimonas | Christensenella | Clostridium disporicum | Clostridium leptum | Clostridium perfringens | Collinsella | Coprococcus | Coriobacteriaceae | Dialister | Dialister invisus | Enterococcus | Erysipelotrichaceae | Eubacterium rectale | Eubacterium ventriosum | Faecalibacterium prausnitzii | Lachnospiraceae | Lactobacillus | Mogibacterium | Odoribacter | Oscillospira | Parabacteroides | Peptococcus | Phascolarctobacterium | Prevotella | Roseburia | Roseburia faecis | Roseburia intestinalis | Ruminiclostridium | Ruminococcaceae | Ruminococcus albus | Streptococcus | Streptococcus salivarius | Subdoligranulum | Turicibacter | Veillonellaceae
Non-alcoholic fatty liver disease 0.0813 13 (0.04) : Citrobacter | Coprococcus | Enterobacteriaceae | Enterococcus | Escherichia | Lachnospiraceae | Lactobacillus | Peptoniphilus | Propionibacterium acnes | Proteobacteria | Ruminococcus | Streptococcus | Veillonella 34 (0.12) : Alistipes | Anaerostipes | Anaerotruncus | Bacillus | Bacteroides | Bacteroides fragilis | Bifidobacterium adolescentis | Bifidobacterium longum | Bilophila | Blautia | Citrobacter | Clostridium | Coprococcus | Dorea | Erysipelotrichaceae | Faecalibacterium | Faecalibacterium prausnitzii | Lactobacillus | Lactococcus | Mogibacterium | Moryella | Odoribacter | Oscillibacter | Oscillospira | Parabacteroides | Prevotella | Pseudomonas | Rikenellaceae | Roseburia | Ruminiclostridium | Ruminococcaceae | Ruminococcus | Ruminococcus gnavus | Turicibacter
Cirrhosis 0.0782 25 (0.08) : Acidaminococcus | Bacteroides vulgatus | Burkholderia | Clostridium | Enterobacteriaceae | Enterococcus | Escherichia coli | Fusobacterium | Haemophilus | Haemophilus parainfluenzae | Klebsiella | Lactobacillus | Prevotella | Proteobacteria | Proteus | Pseudomonas | Ruminococcus | Ruminococcus gnavus | Streptococcus | Streptococcus anginosus | Streptococcus salivarius | Veillonella | Veillonella atypica | Veillonella dispar | Veillonella parvula 32 (0.08) : Akkermansia | Alistipes putredinis | Bacteriodes uniformis | Bacteroides | Bacteroides eggerthii | Bifidobacterium | Bifidobacterium catenulatum | Bifidobacterium longum | Blautia | Coriobacteriaceae | Dehalobacterium | Dorea | Eubacterium hallii | Eubacterium rectale | Faecalibacterium prausnitzii | Fusobacteria | Haemophilus | Lachnospira | Lachnospiraceae | Methanobrevibacter | Mogibacterium | Neisseria | Pleosporales | Prevotella | Rikenellaceae | Roseburia faecis | Roseburia hominis | Roseburia intestinalis | Ruminococcaceae | Ruminococcus | Subdoligranulum | Veillonellaceae
Short Bowel Syndrome 0.0781 14 (0.07) : Citrobacter | Enterobacteriaceae | Enterococcus | Escherichia | Fusobacterium | Haemophilus | Klebsiella | Lachnoanaerobaculum | Lactobacillus | Prevotella | Proteus | Shigella | Streptococcus | Veillonella 22 (0.08) : Akkermansia | Alistipes | Anaerostipes | Bacteroides | Bacteroidetes | Blautia | Clostridium coccoides group | Clostridium leptum | Collinsella | Dorea | Erysipelotrichaceae | Faecalibacterium | Gemella | Lachnospira | Lachnospiraceae | Lactobacillus | Megasphaera | Parabacteroides | Prevotella | Roseburia | Ruminiclostridium | Ruminococcaceae
Alcoholism 0.0780 24 (0.09) : Acidaminococcus | Actinomyces | Candida albicans | Citrobacter | Clostridium | Collinsella | Eikenella | Enterobacteriaceae | Enterococcus | Epulopiscium | Escherichia | Haemophilus | Klebsiella | Lachnospiraceae | Lactobacillus | Morganella | Odoribacter | Prevotella | Proteobacteria | Rothia | Staphylococcus | Streptococcus | Turicibacter | Veillonella 17 (0.07) : Adlercreutzia | Akkermansia | Anaerostipes | Bacteroidetes | Bifidobacterium | Blautia | Collinsella | Coprococcus | Coriobacteriaceae | Dorea | Faecalibacterium | Lachnospiraceae | Mitsuokella | Odoribacter | Peptococcus | Prevotella | Ruminococcus
Hepatocellular cancer 0.0734 21 (0.06) : Acidaminococcus | Actinomyces | Anaerostipes | Anaerotruncus | Clostridium | Collinsella | Coprococcus | Eggerthella | Enterococcus | Escherichia coli | Fusobacterium | Lachnospiraceae | Odoribacter | Prevotella | Proteobacteria | Proteus | Pseudomonas | Ruminococcus | Shigella | Streptococcus | Veillonella 17 (0.08) : Adlercreutzia | Akkermansia | Bacteroidetes | Bifidobacterium | Collinsella | Coprobacillus | Dialister | Enterococcus | Haemophilus | Klebsiella | Lactobacillus | Megasphaera | Pasteurellaceae | Peptococcus | Phascolarctobacterium | Pseudomonas | Streptococcus
Cystic fibrosis 0.0716 19 (0.07) : Aeromonas | Blautia | Clostridioides difficile | Enterobacteriaceae | Enterococcus | Enterococcus faecium | Escherichia coli | Lachnospiraceae | Lactobacillales | Pseudomonas | Ruminococcus gnavus | Shigella | Staphylococcus | Staphylococcus aureus | Streptococcus | Veillonella | Veillonella atypica | Veillonella dispar | Veillonella parvula 35 (0.08) : Akkermansia muciniphila | Alistipes | Alistipes putredinis | Anaerostipes hadrus | Bacteriodes uniformis | Bacteroides | Bacteroides vulgatus | Bacteroidetes | Bifidobacterium | Bifidobacterium adolescentis | Bifidobacterium catenulatum | Blautia | Collinsella aerofaciens | Dialister | Dialister invisus | Erysipelotrichaceae | Eubacterium rectale | Faecalibacterium | Faecalibacterium prausnitzii | Firmicutes | Gemella | Lachnospiraceae | Neisseria | Odoribacter | Pasteurellaceae | Peptococcus | Prevotella | Roseburia | Roseburia hominis | Roseburia intestinalis | Roseburia inulinivorans | Ruminococcaceae | Ruminococcus bromii | Ruminococcus gnavus | Sphingobacterium
Inflamatory bowel disease 0.0696 10 (0.03) : Bacteroides fragilis | Bacteroides vulgatus | Candida albicans | Enterobacteriaceae | Enterococcus | Prevotella | Ruminococcus gnavus | Ruminococcus torques | Sphingomonas | Streptococcus anginosus 23 (0.11) : Alistipes | Anaerostipes | Bacteroides | Bifidobacterium | Blautia | Christensenellaceae | Coprococcus | Coriobacteriaceae | Desulfovibrio | Eubacterium rectale | Faecalibacterium | Faecalibacterium prausnitzii | Lachnobacterium | Methanobrevibacter | Mogibacterium | Parabacteroides | Prevotella | Rikenellaceae | Roseburia hominis | Ruminococcaceae | Ruminococcus | Ruminococcus bromii | Saccharomyces cerevisiae
Chronic kidney disease 0.0683 17 (0.04) : Acinetobacter | Actinomyces | Anaerotruncus | Bifidobacterium | Citrobacter | Eggerthella | Enterobacteriaceae | Escherichia coli | Lactobacillus | Lactobacillus fermentum | Pseudomonas | Rothia | Ruminococcus gnavus | Ruminococcus torques | Shigella | Streptococcus | Streptococcus mutans 28 (0.10) : Akkermansia | Bacteroides | Bacteroides fragilis | Bifidobacterium | Clostridium | Clostridium coccoides group | Collinsella | Coprococcus | Dialister | Dorea | Enterobacter | Enterococcus | Eubacterium hallii | Eubacterium rectale | Faecalibacterium | Faecalibacterium prausnitzii | Hallella | Lachnospira | Pasteurellaceae | Prevotella | Pseudomonas | Rikenellaceae | Roseburia | Ruminococcaceae | Ruminococcus | Stenotrophomonas | Streptococcus | Subdoligranulum
Primary biliary cholangitis 0.0669 12 (0.07) : Citrobacter | Clostridium | Enterobacteriaceae | Fusobacterium | Haemophilus | Klebsiella | Lactobacillales | Lactobacillus | Prevotella | Pseudomonas | Streptococcus | Veillonella 13 (0.06) : Akkermansia | Bacteroides | Bacteroidetes | Barnesiellaceae | Blautia | Butyricimonas | Christensenellaceae | Dialister | Faecalibacterium | Odoribacter | Oscillospira | Phascolarctobacterium | Rikenellaceae
Primary sclerosing cholangitis-IBD 0.0640 19 (0.08) : Acidaminococcus | Acinetobacter | Bifidobacterium | Clostridium | Collinsella | Enterococcus | Escherichia | Fusobacterium | Haemophilus | Lachnospiraceae | Lactobacillus | Rothia | Ruminococcus | Sphingomonas | Staphylococcus | Streptococcus | Veillonella | Veillonella dispar | Veillonella parvula 10 (0.04) : Bacteroides | Blautia | Dorea | Faecalibacterium prausnitzii | Lachnospira | Parabacteroides | Phascolarctobacterium | Prevotella | Roseburia | Ruminococcus gnavus
Chronic alcoholic pancreatitis 0.0622 8 (0.04) : Acinetobacter | Clostridium | Enterococcus | Epulopiscium | Pseudomonas | Sphingomonas | Staphylococcus | Streptococcus 16 (0.09) : Anaerostipes | Bacteroides | Bilophila | Blautia | Desulfovibrio | Dialister | Faecalibacterium | Lachnospira | Lactococcus | Odoribacter | Oscillospira | Parabacteroides | Paraprevotella | Prevotella | Roseburia | Ruminococcus
Parkinson's Disease 0.0590 30 (0.05) : Acidaminococcus | Acinetobacter | Anaerotruncus | Barnesiellaceae | Bifidobacterium | Blautia | Candida albicans | Citrobacter | Clostridium cluster XIVa | Coprococcus | Enterobacteriaceae | Enterococcus | Gardnerella vaginalis | Klebsiella | Lachnobacterium | Lachnospiraceae | Lactobacillus | Lactobacillus fermentum | Morganella | Odoribacter | Prevotella | Proteobacteria | Proteus | Ruminococcus | Ruminococcus torques | Shigella | Sphingomonas | Streptococcus | Streptococcus mutans | Veillonella 32 (0.07) : Bacteroides fragilis | Bacteroides massiliensis | Blautia | Blautia coccoides | Clostridium | Clostridium leptum | Collinsella | Coprococcus | Coprococcus eutactus | Dorea | Eubacterium hallii | Faecalibacterium | Faecalibacterium prausnitzii | Gemella | Haemophilus | Holdemanella | Lachnospira | Lachnospiraceae | Lactobacillus | Limnobacter | Methanobrevibacter | Neisseria | Pasteurellaceae | Prevotella | Roseburia | Roseburia intestinalis | Ruminococcaceae | Ruminococcus | Ruminococcus callidus | Sphingobacterium | Stenotrophomonas | Streptococcus
Type 1 diabetes 0.0570 15 (0.05) : Bacteroides fragilis | Bacteroides ovatus | Bacteroides vulgatus | Bifidobacterium | Blautia | Candida | Candida albicans | Clostridium | Enterobacteriaceae | Escherichia coli | Prevotella | Roseburia hominis | Ruminococcus | Streptococcus | Veillonella 21 (0.07) : Akkermansia | Akkermansia muciniphila | Alistipes | Anaerostipes | Bacteroides fragilis | Bacteroides vulgatus | Bifidobacterium | Blautia coccoides | Clostridium cluster IV | Dialister | Eubacterium rectale | Faecalibacterium | Faecalibacterium prausnitzii | Haemophilus | Lachnospira | Lachnospiraceae | Lactobacillus | Pasteurellaceae | Prevotella | Roseburia | Roseburia faecis
Multiple Sclerosis 0.0569 17 (0.04) : Actinomyces | Anaerotruncus | Bacteroides fragilis | Bifidobacterium | Blautia | Clostridium | Collinsella | Coprococcus | Eggerthella | Faecalicoccus | Haemophilus | Lactobacillus | Proteobacteria | Ruminococcus | Shigella | Streptococcus | Streptococcus salivarius 22 (0.07) : Anaerostipes hadrus | Bacillus | Bacteroides | Blautia | Butyricimonas | Clostridium | Dialister | Dorea | Erysipelotrichaceae | Eubacterium rectale | Faecalibacterium | Faecalibacterium prausnitzii | Firmicutes | Fusobacteria | Gemmiger | Lachnospira | Lachnospiraceae | Prevotella | Pseudomonas | Roseburia | Ruminococcaceae | Sporobacter
Primary sclerosing cholangitis 0.0536 13 (0.05) : Clostridium | Enterococcus | Enterococcus faecium | Escherichia coli | Fusobacterium | Haemophilus | Lactobacillus | Morganella | Staphylococcus | Streptococcus | Veillonella | Veillonella dispar | Veillonella parvula 15 (0.06) : Anaerostipes | Blautia | Christensenellaceae | Coprococcus | Desulfovibrio | Faecalibacterium | Faecalibacterium prausnitzii | Haemophilus | Lachnospiraceae | Parabacteroides | Phascolarctobacterium | Ruminiclostridium | Ruminococcus | Ruminococcus gnavus | Saccharomyces cerevisiae
Cholestasis 0.0470 8 (0.05) : Clostridium | Clostridium butyricum | Enterobacteriaceae | Enterococcus | Staphylococcus | Streptococcus | Streptococcus salivarius | Veillonella 11 (0.05) : Anaerostipes | Bacteroides | Bacteroides fragilis | Bifidobacterium | Blautia | Collinsella | Faecalibacterium | Faecalibacterium prausnitzii | Flavonifractor plautii | Roseburia | Ruminococcus gnavus
Rheumatoid Arthritis 0.0469 18 (0.04) : Actinomyces | Clostridium | Collinsella | Eggerthella | Faecalicoccus | Fusobacterium | Gardnerella vaginalis | Haemophilus | Haemophilus parainfluenzae | Klebsiella | Lactobacillus | Prevotella | Prevotella melaninogenica | Rothia | Staphylococcus aureus | Streptococcus | Veillonella | Veillonella dispar 20 (0.05) : Anaerofustis | Bacteroides | Bacteroides fragilis | Bifidobacterium | Collinsella | Coriobacteriaceae | Defluviitalea | Erysipelotrichaceae | Eubacterium rectale | Gemella | Gemmiger | Haemophilus | Lachnospira | Prevotella | Pseudomonas | Roseburia | Roseburia faecis | Sporobacter | Stenotrophomonas | Streptococcus
Hepatitis B 0.0464 10 (0.04) : Actinomyces | Clostridium | Enterobacteriaceae | Fusobacterium | Haemophilus | Lactobacillus | Prevotella | Ruminococcus | Streptococcus | Veillonella 14 (0.05) : Alistipes | Anaerostipes | Asaccharobacter | Bacteroides | Bifidobacterium | Butyricimonas | Clostridium cluster IV | Faecalibacterium prausnitzii | Megasphaera | Parabacteroides | Paraprevotella | Phascolarctobacterium | Prevotella | Ruminococcus
Coronary artery disease 0.0463 15 (0.04) : Actinobacillus | Barnesiellaceae | Collinsella | Enterococcus | Haemophilus | Klebsiella | Lactobacillales | Lactobacillus | Odoribacter | Parabacteroides distasonis | Prevotella | Pseudomonas | Ruminococcus gnavus | Shigella | Streptococcus 16 (0.05) : Bacteroides | Blautia | Christensenellaceae | Coprococcus | Dorea | Enterobacter | Erysipelotrichaceae | Eubacterium hallii | Eubacterium rectale | Faecalibacterium | Lachnospira | Lachnospiraceae | Roseburia | Ruminococcaceae | Streptococcus | Subdoligranulum
Alzheimer's disease 0.0461 10 (0.03) : Bacteroides vulgatus | Bifidobacterium | Blautia | Enterobacteriaceae | Escherichia | Lactobacillus | Proteobacteria | Pseudomonas | Shigella | Streptococcus 18 (0.07) : Adlercreutzia | Alistipes | Bacteroides | Bacteroides fragilis | Bacteroidetes | Bifidobacterium | Blautia | Clostridium | Dialister | Eubacterium rectale | Firmicutes | Lachnospiraceae | Parabacteroides | Paraprevotella | Ruminococcus | Subdoligranulum | Turicibacter | Veillonellaceae
Non alcoholic steatohepatitis 0.0459 6 (0.02) : Blautia | Escherichia | Lactobacillus | Peptoniphilus | Prevotella | Ruminococcus 13 (0.07) : Alistipes | Bacteroidetes | Bifidobacterium | Bifidobacterium adolescentis | Bifidobacterium longum | Blautia | Clostridium leptum | Coprococcus | Eubacterium | Oscillospira | Roseburia | Ruminococcaceae | Ruminococcus
Celiac Disease 0.0455 13 (0.04) : Bacteroides vulgatus | Bacteroides-Prevotella group | Coprococcus | Enterobacteriaceae | Escherichia coli | Klebsiella | Lachnospiraceae | Lactobacillus | Parabacteroides distasonis | Prevotella | Shigella | Staphylococcus | Veillonella parvula 19 (0.05) : Akkermansia | Anaerostipes | Bacteroidetes | Bifidobacterium | Blautia | Clostridium lituseburense | Dorea | Enterococcus | Faecalibacterium prausnitzii | Firmicutes | Fusobacteria | Gemella | Lachnospiraceae | Lactobacillus | Megasphaera | Mogibacterium | Prevotella | Streptococcus mitis | Veillonellaceae
Autoimmune hepatitis 0.0439 5 (0.04) : Klebsiella | Lactobacillales | Lactobacillus | Streptococcus | Veillonella 9 (0.05) : Bifidobacterium | Clostridiales | Coprococcus | Lactobacillus | Oscillospira | Parabacteroides | Rikenellaceae | Ruminococcaceae | Streptococcus
Gastric carcinoma 0.0439 17 (0.06) : Acinetobacter | Bifidobacterium | Citrobacter | Clostridium | Fusobacterium | Haemophilus parainfluenzae | Klebsiella | Lachnospiraceae | Lactobacillus | Peptostreptococcus | Prevotella | Prevotella melaninogenica | Propionibacterium acnes | Shigella | Streptococcus | Streptococcus anginosus | Veillonella 10 (0.03) : Bacteriodes uniformis | Bacteroides | Eubacterium rectale | Faecalibacterium | Helicobacter | Lachnospira | Neisseria | Prevotella | Roseburia | Streptococcus
Hypertension 0.0438 10 (0.03) : Actinomyces | Bifidobacterium | Clostridium | Eggerthella | Fusobacterium | Klebsiella | Lactobacillus | Prevotella | Shigella | Streptococcus 14 (0.05) : Bifidobacterium | Blautia | Clostridium | Coprococcus | Dorea | Enterococcus | Eubacterium rectale | Faecalibacterium | Klebsiella | Odoribacter | Oscillibacter | Oscillospira | Roseburia | Ruminococcus callidus
Ankylosing spondylitis 0.0436 12 (0.04) : Actinomyces | Bifidobacterium | Blautia | Collinsella | Eggerthella | Escherichia coli | Flavonifractor plautii | Lachnospiraceae | Parabacteroides distasonis | Prevotella | Rothia | Streptococcus 12 (0.05) : Citrobacter | Clostridium | Enterobacter | Enterococcus | Eubacterium | Klebsiella | Lachnospira | Odoribacter | Parabacteroides | Roseburia | Ruminococcus | Veillonellaceae
Glycogen storage disease 0.0430 4 (0.02) : Bifidobacterium | Lactobacillus | Ruminococcus gnavus | Shigella 11 (0.06) : Alistipes | Anaerostipes | Blautia | Christensenellaceae | Coprococcus | Eubacterium hallii | Faecalibacterium | Methanobrevibacter | Odoribacter | Phascolarctobacterium | Roseburia
Pulmonary tubercolosis 0.0412 12 (0.04) : Acinetobacter | Clostridium boltae | Collinsella | Coprococcus | Escherichia | Escherichia coli | Faecalibacterium prausnitzii | Lactobacillus | Proteobacteria | Staphylococcus | Streptococcus | Veillonella dispar 15 (0.04) : Akkermansia muciniphila | Bacteroidetes | Bifidobacterium adolescentis | Bifidobacterium longum | Collinsella aerofaciens | Coprococcus | Eubacterium rectale | Gemella | Lachnospira | Prevotella | Roseburia | Roseburia hominis | Roseburia intestinalis | Roseburia inulinivorans | Streptococcus
Psoriasis 0.0398 21 (0.04) : Actinomyces | Bacteroides vulgatus | Bifidobacterium | Blautia | Collinsella | Coprococcus | Enterococcus | Finegoldia | Flavobacterium | Lachnospiraceae | Lactobacillales | Malassezia restricta | Peptostreptococcus | Prevotella | Proteobacteria | Pseudomonas | Ruminococcus | Ruminococcus gnavus | Sphingomonas | Staphylococcus | Streptococcus 17 (0.04) : Akkermansia muciniphila | Alistipes | Bacteroides | Bacteroidetes | Coprobacillus | Coprococcus | Coriobacteriaceae | Faecalibacterium | Firmicutes | Gordonibacter | Lachnospira | Lachnospiraceae | Lactobacillus | Parabacteroides | Paraprevotella | Ruminococcaceae | Streptococcus
Lung cancer 0.0397 11 (0.04) : Bifidobacterium | Coprococcus | Enterobacteriaceae | Enterococcus | Lachnospiraceae | Odoribacter | Parabacteroides distasonis | Prevotella | Ruminococcus gnavus | Sphingomonas | Streptococcus 11 (0.04) : Bifidobacterium | Bifidobacterium adolescentis | Bifidobacterium longum | Clostridium | Coriobacteriaceae | Erysipelotrichaceae | Faecalibacterium prausnitzii | Parabacteroides | Roseburia faecis | Ruminococcus bromii | Streptococcus
Acquired Immunodeficiency Syndrome 0.0394 4 (0.02) : Enterococcus | Lactobacillus | Ruminococcus | Streptococcus 12 (0.06) : Bacteriodes uniformis | Bacteroides vulgatus | Blautia | Dialister | Faecalibacterium | Lachnospira | Prevotella | Roseburia | Ruminiclostridium | Ruminococcus | Ruminococcus bromii | Ruminococcus callidus
Pancreatic Cancer 0.0385 7 (0.01) : Acidaminococcus | Haemophilus | Klebsiella | Lachnospiraceae | Lactobacillus | Prevotella | Veillonella 18 (0.06) : Akkermansia | Alistipes | Anaerostipes | Anaerotruncus | Bifidobacterium | Bilophila | Blautia | Clostridium cluster IV | Coprococcus | Dorea | Faecalibacterium | Gemmiger | Megasphaera | Mogibacterium | Parabacteroides | Ruminococcaceae | Sporobacter | Streptococcus mitis
Sjögren syndrome 0.0381 15 (0.04) : Bacteroides ovatus | Bacteroides vulgatus | Bifidobacterium | Blautia | Candida albicans | Clostridium | Escherichia | Fusobacterium nucleatum | Lactobacillus | Prevotella | Staphylococcus aureus | Streptococcus | Streptococcus mutans | Streptococcus salivarius | Veillonella 16 (0.03) : Alistipes | Bacteroides | Bifidobacterium | Blautia | Clostridium | Dorea | Enterococcus | Faecalibacterium | Haemophilus | Moryella | Neisseria | Parabacteroides | Peptococcus | Prevotella | Roseburia | Ruminococcus
Major depressive disorder 0.0379 6 (0.01) : Actinomyces | Anaerostipes | Blautia | Eggerthella | Streptococcus | Veillonella 14 (0.06) : Bacteroides | Bifidobacterium | Blautia | Clostridium | Coprococcus | Dialister | Eubacterium | Faecalibacterium | Lachnospiraceae | Lactobacillus | Oscillibacter | Phascolarctobacterium | Prevotella | Ruminococcus
Polycystic ovary syndrome 0.0373 6 (0.03) : Bacteroides ovatus | Bacteroides vulgatus | Finegoldia | Fusobacteria | Lactobacillus | Prevotella 10 (0.05) : Akkermansia | Bacteroides | Clostridium cluster IV | Faecalibacterium | Lactobacillus | Lactococcus | Oscillibacter | Parabacteroides | Prevotella | Ruminococcaceae
Severe fever with thrombocytopenia syndrome 0.0356 6 (0.03) : Coprococcus | Enterococcus | Escherichia | Lactobacillus | Streptococcus | Veillonella 6 (0.04) : Anaerostipes | Blautia | Faecalibacterium | Lachnospira | Prevotella | Ruminococcus
Alcoholic Hepatitis 0.0354 10 (0.03) : Actinomyces | Bifidobacterium | Candida | Enterobacteriaceae | Enterococcus | Haemophilus | Lactobacillus | Rothia | Streptococcus | Veillonella 11 (0.04) : Akkermansia | Bacteroides | Bacteroidetes | Bilophila | Christensenellaceae | Desulfovibrio | Odoribacter | Oscillospira | Parabacteroides | Prevotella | Ruminococcus
Generalized anxiety disorder 0.0353 6 (0.03) : Burkholderia | Enterobacteriaceae | Fusobacterium | Ruminococcus gnavus | Shigella | Tyzzerella 13 (0.04) : Bacteroides | Bacteroides xylanolyticus | Coprococcus | Dialister | Eubacterium rectale | Faecalibacterium | Holdemanella | Lachnospira | Lachnospiraceae | Mitsuokella | Prevotella | Ruminococcaceae | Subdoligranulum
Oral cancer 0.0346 18 (0.06) : Actinomyces | Candida albicans | Capnocytophaga | Clostridium | Enterobacteriaceae | Fusobacterium | Haemophilus | Lactobacillus | Peptostreptococcus | Prevotella | Prevotella melaninogenica | Rothia | Staphylococcus aureus | Streptococcus | Streptococcus anginosus | Streptococcus salivarius | Veillonella | Veillonella parvula 5 (0.00) : Firmicutes | Haemophilus | Streptococcus | Streptococcus mitis | Streptococcus salivarius
Covid-19 0.0346 8 (0.03) : Actinomyces | Blautia | Candida albicans | Clostridium ramosum | Proteobacteria | Rothia | Streptococcus | Veillonella 11 (0.04) : Anaerostipes | Blautia | Coprococcus | Eubacterium hallii | Eubacterium rectale | Eubacterium ventriosum | Faecalibacterium | Faecalibacterium prausnitzii | Lachnospiraceae | Roseburia | Ruminococcaceae
Microscopic colitis 0.0345 3 (0.01) : Haemophilus parainfluenzae | Lachnospiraceae | Veillonella parvula 13 (0.06) : Akkermansia | Akkermansia muciniphila | Alistipes putredinis | Anaerotruncus | Christensenellaceae | Clostridium | Coprococcus | Coriobacteriaceae | Enterobacter | Prevotella | Ruminiclostridium | Ruminococcus | Subdoligranulum
Preeclamsia 0.0341 10 (0.03) : Blautia | Clostridium | Enterobacteriaceae | Escherichia | Fusobacterium | Listeria | Prevotella | Proteobacteria | Ruminococcus | Veillonella 7 (0.04) : Akkermansia | Dialister | Faecalibacterium | Firmicutes | Gemmiger | Lachnospira | Methanobrevibacter
Thyroid carcinoma 0.0334 11 (0.04) : Anaerostipes | Blautia | Coprococcus | Intestinibacter | Klebsiella | Lactobacillus | Prevotella | Ruminococcus | Shigella | Streptococcus | Turicibacter 8 (0.02) : Bacteroides | Butyricimonas | Christensenellaceae | Phascolarctobacterium | Prevotella | Rikenellaceae | Roseburia | Ruminococcus gnavus
Hepatitis C 0.0327 8 (0.03) : Acinetobacter | Citrobacter | Escherichia | Haemophilus | Lactobacillus | Prevotella | Streptococcus | Veillonella 8 (0.03) : Bilophila | Butyricimonas | Clostridium cluster IV | Mitsuokella | Parabacteroides | Pseudoflavonifractor | Ruminococcus | Vivictivallis
Kidney stone 0.0325 7 (0.02) : Acinetobacter | Bacteroides fragilis | Bacteroides ovatus | Lachnospiraceae | Parabacteroides distasonis | Shigella | Veillonella parvula 12 (0.05) : Anaerostipes | Bilophila | Dialister | Dorea | Eubacterium hallii | Faecalibacterium | Holdemania | Lactobacillus | Prevotella | Ruminiclostridium | Ruminococcus | Subdoligranulum
Biliary atresia 0.0320 4 (0.03) : Enterococcus | Klebsiella | Lactobacillus | Streptococcus 7 (0.03) : Anaerostipes | Bacteroides | Bifidobacterium | Blautia | Faecalibacterium | Haemophilus | Megasphaera
Schizophrenia 0.0319 20 (0.04) : Actinomyces | Anaerotruncus | Bacteroides fragilis | Blautia | Clostridioides difficile | Clostridium | Eggerthella | Enterobacteriaceae | Enterococcus faecium | Escherichia | Klebsiella | Lactobacillus | Lactobacillus fermentum | Ruminococcus gnavus | Shigella | Streptococcus salivarius | Veillonella | Veillonella atypica | Veillonella dispar | Veillonella parvula 12 (0.02) : Clostridium | Coprococcus | Enterococcus | Erysipelotrichaceae | Eubacterium ventriosum | Faecalibacterium | Haemophilus | Lachnospiraceae | Megasphaera | Rikenellaceae | Roseburia faecis | Ruminococcaceae
Stevens-Johnson syndrome 0.0315 15 (0.06) : Acinetobacter | Bifidobacterium | Blautia | Collinsella | Coprococcus | Fusobacterium | Lactobacillus | Odoribacter | Prevotella | Pseudomonas | Ruminococcus | Staphylococcus | Streptococcus | Turicibacter | Veillonella 1 (0.00) : Clostridium
Hand, foot and mouth disease 0.0307 4 (0.03) : Bifidobacterium | Enterococcus | Escherichia | Streptococcus 5 (0.03) : Dorea | Gemmiger | Phascolarctobacterium | Roseburia | Ruminococcus
Amyotrophic lateral sclerosis 0.0292 9 (0.03) : Anaerostipes | Anaerotruncus | Bacteroides vulgatus | Escherichia coli | Lachnospiraceae | Odoribacter | Parabacteroides distasonis | Ruminococcus | Ruminococcus torques 5 (0.03) : Bacteroides | Clostridium | Dorea | Faecalibacterium | Ruminococcus
Pouchitis 0.0284 7 (0.02) : Citrobacter | Clostridium | Enterobacteriaceae | Escherichia | Prevotella | Streptococcus | Veillonella 7 (0.03) : Bacteroides | Faecalibacterium | Lachnospiraceae | Lactobacillus | Parabacteroides | Ruminococcaceae | Streptococcus
Pancreatitis 0.0282 7 (0.02) : Clostridium cluster XIVa | Enterobacteriaceae | Enterococcus | Prevotella | Shigella | Staphylococcus | Stenotrophomonas 9 (0.03) : Bifidobacterium | Blautia | Faecalibacterium | Faecalibacterium prausnitzii | Lachnospiraceae | Lactococcus | Prevotella | Pseudomonas | Ruminococcus bromii
Heart failure 0.0278 6 (0.03) : Anaerostipes | Enterococcus | Fusobacterium | Lactobacillus | Streptococcus | Veillonella 8 (0.03) : Bilophila | Clostridium | Collinsella | Dorea | Eubacterium rectale | Faecalibacterium prausnitzii | Mycobacterium | Oscillibacter
Infantile eczema 0.0269 5 (0.01) : Anaerostipes | Clostridium cluster XIVa | Coprococcus | Shigella | Veillonella 14 (0.05) : Anaerotruncus | Bifidobacterium | Collinsella | Dialister | Dorea | Haemophilus | Klebsiella | Lactobacillus | Megasphaera | Oscillibacter | Prevotella | Ruminococcus | Streptococcus | Turicibacter
Asthma 0.0264 17 (0.04) : Acidaminococcus | Actinomyces | Anaerostipes | Enterobacteriaceae | Escherichia coli | Haemophilus | Klebsiella | Lactobacillus | Odoribacter | Proteobacteria | Pseudomonas | Rothia | Ruminococcus | Stenotrophomonas | Streptococcus | TM7 | Veillonella 11 (0.01) : Bifidobacterium | Dialister | Enterococcus | Faecalibacterium | Lachnospira | Mycobacterium | Neisseria | Paludibacter | Peptococcus | Prevotella | Streptococcus
Arsenic exposure 0.0263 4 (0.03) : Blautia | Enterococcus | Ruminococcus | Streptococcus 5 (0.02) : Bacteroides | Bifidobacterium | Coprococcus | Parabacteroides | Rikenellaceae
Macular degeneration 0.0258 10 (0.05) : Actinomyces | Anaerotruncus | Finegoldia | Peptoniphilus | Prevotella | Rothia | Ruminococcus torques | Staphylococcus | Streptococcus | Veillonella 2 (0.01) : Bacteroides eggerthii | Prevotella
Graves' disease 0.0254 2 (0.01) : Haemophilus | Prevotella 8 (0.04) : Alistipes | Bifidobacterium | Eubacterium | Faecalibacterium | Lactobacillus | Parabacteroides | Rikenellaceae | Veillonellaceae
Human end-stage renal disease 0.0254 3 (0.01) : Flavonifractor plautii | Fusobacterium | Ruminococcus 9 (0.04) : Bacillus | Bifidobacterium | Clostridium | Dialister | Eubacterium rectale | Faecalibacterium prausnitzii | Lachnospira | Megasphaera | Roseburia
Chronic Obstructive Pulmonary Disease 0.0253 17 (0.04) : Actinomyces | Aeromonas | Bifidobacterium | Burkholderia | Capnocytophaga | Fusobacterium | Haemophilus | Lactobacillus | Peptostreptococcus | Prevotella | Pseudomonas | Rothia | Stenotrophomonas | Streptococcus | TM7 | Veillonella | Veillonella dispar 8 (0.01) : Bacteroidetes | Citrobacter | Clostridium | Gemella | Neisseria | Pasteurellaceae | Prevotella | Streptococcus
Atopic Dermatitis 0.0251 8 (0.02) : Clostridioides difficile | Clostridium leptum | Escherichia coli | Faecalibacterium prausnitzii | Lactobacillus | Staphylococcus | Staphylococcus aureus | Streptococcus 15 (0.03) : Akkermansia | Bacteroides fragilis | Bacteroides vulgatus | Bifidobacterium | Blautia | Clostridium | Coprococcus | Coprococcus eutactus | Enterococcus | Eubacterium | Klebsiella | Lactobacillus | Limnobacter | Pseudomonas | Streptococcus
Idiopathic focal epilepsy 0.0250 1 (0.00) : Haemophilus 8 (0.05) : Bacteroides | Bifidobacterium | Blautia | Collinsella | Coprococcus | Faecalibacterium | Parabacteroides | Ruminococcus
Gestational diabetes 0.0245 11 (0.04) : Actinomyces | Collinsella | Enterococcus | Klebsiella | Lachnospiraceae | Parabacteroides distasonis | Prevotella | Rothia | Shigella | Tyzzerella | Veillonella 7 (0.01) : Dialister | Lactobacillus | Megasphaera | Parabacteroides | Prevotella | Ruminococcaceae | Ruminococcus
Acne 0.0244 7 (0.02) : Enterobacteriaceae | Enterococcus | Klebsiella | Odoribacter | Proteobacteria | Ruminococcus | Staphylococcus 13 (0.03) : Bacillus | Bifidobacterium | Bilophila | Blautia | Coprobacillus | Gemmiger | Lachnospira | Lactobacillus | Lactococcus | Oxalobacter | Paenibacillus | Paraprevotella | Ruminococcus
Systemic lupus erythematosus 0.0240 16 (0.04) : Actinomyces | Bacteroides ovatus | Bacteroides vulgatus | Eggerthella | Fusobacterium | Klebsiella | Lachnospiraceae | Lactobacillales | Lactobacillus | Prevotella | Pseudomonas | Rothia | Ruminococcus gnavus | Staphylococcus aureus | Streptococcus anginosus | Veillonella dispar 6 (0.01) : Alistipes indistinctus | Bifidobacterium | Clostridium | Faecalibacterium prausnitzii | Prevotella | Roseburia
Bladder cancer 0.0239 9 (0.03) : Acinetobacter | Aeromonas | Fusobacterium | Fusobacterium nucleatum | Pelomonas | Proteobacteria | Roseburia hominis | Shigella | Sphingomonas 8 (0.02) : Bacteroides | Bifidobacterium | Firmicutes | Lactobacillus | Prevotella | Ruminiclostridium | Ruminococcaceae | Streptococcus
Rett Syndrome 0.0233 2 (0.01) : Bifidobacterium | Blautia 6 (0.04) : Alistipes | Bacteroides | Faecalibacterium | Gemmiger | Ruminococcus | Streptococcus
Uveitits 0.0230 7 (0.03) : Burkholderia | Candida glabrata | Malassezia globosa | Malassezia restricta | Prevotella | Streptococcus | Veillonella 11 (0.02) : Bacteroides | Barnesiellaceae | Blautia | Dorea | Faecalibacterium | Lachnospira | Odoribacter | Pleosporales | Pseudomonas | Roseburia | Ruminococcus
Smoking 0.0228 15 (0.04) : Actinobacillus | Actinomyces | Bifidobacterium | Capnocytophaga | Fusobacterium | Fusobacterium nucleatum | Lactobacillus | Parvimonas micra | Prevotella | Rothia | Staphylococcus | Streptococcus | Streptococcus salivarius | Veillonella | Veillonella dispar 7 (0.01) : Gemella | Haemophilus | Lactobacillus | Neisseria | Peptococcus | Prevotella | Streptococcus
Metabolic syndrome 0.0225 2 (0.01) : Coprococcus | Turicibacter 8 (0.04) : Bifidobacterium | Desulfovibrio | Faecalibacterium prausnitzii | Roseburia intestinalis | Roseburia inulinivorans | Ruminococcus flavefaciens | Subdoligranulum | Turicibacter
Gestational diabetes + hyperlipidemia 0.0224 5 (0.04) : Actinomyces | Haemophilus | Prevotella | Streptococcus | Veillonella 1 (0.01) : Faecalibacterium
Attention Deficit Hyperactivity Disorder 0.0223 5 (0.01) : Bacteroides caccae | Bacteroides ovatus | Bifidobacterium | Fusobacterium | Veillonella parvula 7 (0.03) : Clostridiales | Dialister | Faecalibacterium | Faecalibacterium prausnitzii | Lachnospiraceae | Lactobacillus | Ruminococcus gnavus
Atopic wheeze 0.0216 4 (0.03) : Clostridioides difficile | Ruminococcus gnavus | Streptococcus | Veillonella 2 (0.01) : Bacteroides | Bifidobacterium
Keratitis 0.0213 1 (0.00) : Bacteroides fragilis 12 (0.04) : Bifidobacterium adolescentis | Clostridium | Dialister | Dorea | Faecalibacterium | Faecalibacterium prausnitzii | Klebsiella | Lachnospira | Megasphaera | Mitsuokella | Roseburia | Ruminococcus
Cardiac valve calcification 0.0212 4 (0.02) : Enterococcus | Fusobacterium | Lactobacillus | Veillonella dispar 5 (0.02) : Bacteroides | Blautia | Dorea | Erysipelotrichaceae | Ruminococcaceae
Behcet's Disease 0.0211 7 (0.02) : Acidaminococcus | Bifidobacterium | Eggerthella | Fusobacterium | Haemophilus parainfluenzae | Rothia | Streptococcus 13 (0.02) : Alistipes | Anaerotruncus | Bacteroidetes | Clostridiales | Clostridium | Coprococcus | Dialister invisus | Eubacterium | Lachnospiraceae | Neisseria | Prevotella | Roseburia | Subdoligranulum
Ischemic stroke 0.0208 2 (0.00) : Enterobacteriaceae | Enterococcus 7 (0.04) : Anaerostipes | Bacteroides | Blautia | Clostridium coccoides group | Faecalibacterium | Lachnospiraceae | Roseburia
Allergy 0.0206 3 (0.01) : Blautia | Clostridium | Ruminococcus gnavus 6 (0.03) : Bacteroides | Coprococcus | Enterococcus | Lachnospira | Lactobacillus | Prevotella
Atherosclerosis 0.0205 7 (0.02) : Collinsella | Enterobacteriaceae | Escherichia coli | Fusobacterium nucleatum | Klebsiella | Ruminococcus gnavus | Streptococcus 6 (0.02) : Bacteroides | Eubacterium | Faecalibacterium prausnitzii | Roseburia | Roseburia intestinalis | Roseburia inulinivorans
Caries 0.0205 19 (0.03) : Acinetobacter | Actinomyces | Candida albicans | Capnocytophaga | Cryptococcus neoformans | Haemophilus | Lachnospiraceae | Lactobacillus | Lactobacillus fermentum | Prevotella | Prevotella melaninogenica | Pseudomonas | Streptococcus | Streptococcus mutans | Streptococcus salivarius | Veillonella | Veillonella atypica | Veillonella dispar | Veillonella parvula 10 (0.01) : Bacteroidetes | Haemophilus | Lachnospiraceae | Naganishia | Neisseria | Peptococcus | Prevotella | Pseudomonas | Streptococcus | Streptococcus mitis
Spinal cord injury 0.0204 3 (0.01) : Blautia | Escherichia coli | Shigella 7 (0.03) : Dialister | Eubacterium rectale | Faecalibacterium | Lactobacillus | Prevotella | Roseburia | Subdoligranulum
Hashimoto's thyroiditis 0.0204 3 (0.01) : Blautia | Escherichia coli | Ruminococcus torques 7 (0.03) : Bacteroides | Bifidobacterium | Dialister | Faecalibacterium | Lactobacillus | Prevotella | Veillonellaceae
Colon adenomas 0.0199 6 (0.02) : Fusobacterium | Proteobacteria | Pseudomonas | Ruminococcus | Shigella | Veillonella 8 (0.02) : Bacteroides | Butyricimonas | Collinsella | Coprococcus | Firmicutes | Lachnobacterium | Mitsuokella | Oscillibacter
Fibromyalgia 0.0196 1 (0.00) : Flavonifractor plautii 8 (0.04) : Bacteriodes uniformis | Bacteroides | Bifidobacterium | Blautia faecis | Clostridium | Eubacterium | Faecalibacterium prausnitzii | Lachnospiraceae
Chagas' disease 0.0195 7 (0.04) : Actinobacillus | Blautia | Enterococcus | Fusobacterium | Lactobacillus | Streptococcus | Veillonella 1 (0.00) : Bacteroides
Collagenous colitis 0.0195 1 (0.00) : Lachnospiraceae 7 (0.04) : Akkermansia | Alistipes | Clostridium cluster IV | Collinsella | Coprococcus | Oscillibacter | Ruminococcaceae
Common Variable Immunodeficieny 0.0194 4 (0.02) : Anaerotruncus | Eggerthella | Enterobacteriaceae | Streptococcus 3 (0.02) : Clostridiales | Coriobacteriaceae | Mitsuokella
Chronic urticaria 0.0190 1 (0.01) : Enterobacteriaceae 5 (0.03) : Bacteroides | Bifidobacterium | Faecalibacterium | Lactobacillus | Ruminococcaceae
Bipolar disorder 0.0189 1 (0.00) : Proteobacteria 7 (0.04) : Bacteroidetes | Coprococcus | Faecalibacterium | Gemmiger | Roseburia | Ruminococcaceae | Ruminococcus
Helicobacter pylori infection 0.0184 7 (0.02) : Acinetobacter | Candida glabrata | Enterococcus | Haemophilus | Proteobacteria | Sphingomonas | Turicibacter 8 (0.02) : Bacteroides vulgatus | Bacteroidetes | Firmicutes | Fusobacteria | Klebsiella | Peptococcus | Roseburia | Streptococcus
Urogenital Schistosomiasis 0.0184 7 (0.02) : Acinetobacter | Enterococcus | Fusobacterium | Haemophilus | Lactobacillus | Prevotella | Veillonella 6 (0.01) : Bacillus | Erysipelotrichaceae | Janthinobacterium | Parabacteroides | Ruminococcaceae | Subdoligranulum
Pervasive developmental disorder NOS 0.0183 3 (0.00) : Bacteroides fragilis | Collinsella | Faecalibacterium prausnitzii 11 (0.03) : Bacteriodes uniformis | Bacteroides vulgatus | Coprococcus eutactus | Oscillospira | Parabacteroides | Roseburia faecis | Roseburia hominis | Roseburia intestinalis | Ruminococcus gnavus | Streptococcus salivarius | Subdoligranulum
Postmenopausal 0.0177 2 (0.01) : Prevotella | Staphylococcus 5 (0.03) : Alistipes | Eubacterium | Faecalibacterium | Lactobacillus | Roseburia
Hepatic encephalopathy 0.0177 6 (0.02) : Bifidobacterium | Burkholderia | Enterobacteriaceae | Enterococcus | Lactobacillales | Veillonella 6 (0.02) : Clostridiales | Faecalibacterium | Lachnospiraceae | Pasteurellaceae | Roseburia | Ruminococcus
Invasive pneumococcal disease 0.0177 8 (0.04) : Acinetobacter | Actinomyces | Capnocytophaga | Lachnoanaerobaculum | Prevotella | Rothia | Streptococcus | Veillonella 0 (0.00)
COPD Exacerbation 0.0174 3 (0.01) : Acinetobacter | Haemophilus | Proteobacteria 7 (0.02) : Firmicutes | Gemella | Lachnospiraceae | Prevotella | Ruminococcaceae | Streptococcus | Subdoligranulum
Constipation 0.0170 6 (0.02) : Acinetobacter | Blautia | Coprococcus | Enterococcus | Flavobacterium | Ruminococcus 4 (0.01) : Adlercreutzia | Blautia | Odoribacter | Prevotella
Coronary Heart Disease 0.0165 0 (0.00) 7 (0.03) : Bacteroidetes | Citrobacter | Collinsella | Megasphaera | Mitsuokella | Parabacteroides | Prevotella
Juvenile idiopathic arthritis 0.0165 4 (0.01) : Faecalibacterium prausnitzii | Haemophilus parainfluenzae | Klebsiella | Parabacteroides distasonis 6 (0.02) : Barnesiellaceae | Blautia | Enterococcus | Firmicutes | Gemella | Turicibacter
Idiopathic Pulmonary Fibrosis 0.0162 6 (0.02) : Blautia | Haemophilus | Prevotella | Rothia | Streptococcus | Veillonella 3 (0.01) : Coprococcus | Dorea | Paludibacter
Posttraumatic stress syndrome 0.0162 2 (0.01) : Acidaminococcus | Streptococcus 6 (0.03) : Anaerostipes | Lachnospira | Pseudoflavonifractor | Roseburia | Ruminococcus | Subdoligranulum
Maturity-onset diabetes of the young 2 0.0160 1 (0.01) : Prevotella 4 (0.02) : Anaerostipes | Faecalibacterium | Lachnospira | Roseburia
Fibrosis 0.0160 2 (0.01) : Ruminococcus | Streptococcus 4 (0.02) : Bacteroides | Coprococcus | Faecalibacterium prausnitzii | Oscillospira
Migraine 0.0159 7 (0.02) : Clostridium boltae | Clostridium ramosum | Flavonifractor plautii | Lachnospiraceae | Pseudomonas | Ruminococcus gnavus | Streptococcus 2 (0.01) : Bifidobacterium adolescentis | Faecalibacterium prausnitzii
Spondyloarthritis 0.0158 4 (0.02) : Bifidobacterium | Coprococcus | Lachnospiraceae | Ruminococcus gnavus 4 (0.02) : Faecalibacterium prausnitzii | Lachnospiraceae | Roseburia | Ruminococcus
Aphthous ulcer 0.0156 6 (0.02) : Capnocytophaga | Lactobacillus | Prevotella | Shigella | Streptococcus anginosus | Streptococcus salivarius 4 (0.01) : Gemella | Haemophilus | Megasphaera | Streptococcus
Aerobic vaginitis 0.0155 14 (0.03) : Enterococcus | Escherichia | Escherichia coli | Faecalibacterium prausnitzii | Finegoldia | Gardnerella vaginalis | Haemophilus | Lactobacillus fermentum | Prevotella melaninogenica | Staphylococcus | Streptococcus | Streptococcus anginosus | Veillonella | Veillonella dispar 2 (0.00) : Lactobacillus | Lactobacillus coleohominis
Interstitial cystitis 0.0153 3 (0.01) : Bifidobacterium | Enterococcus | Proteus 9 (0.02) : Coprococcus | Dialister | Eubacterium | Faecalibacterium | Lactobacillus | Megasphaera | Prevotella | Ruminococcus | Streptococcus
Primary biliary cirrhosis 0.0149 5 (0.02) : Enterobacteriaceae | Haemophilus parainfluenzae | Klebsiella | Streptococcus | Veillonella 3 (0.01) : Bacteroides eggerthii | Lachnobacterium | Ruminococcus bromii
Aggressive periodontitis 0.0146 6 (0.01) : Fusobacterium nucleatum | Parvimonas micra | Peptostreptococcus | Prevotella | TM7 | Veillonella 14 (0.02) : Akkermansia | Bacteroides | Bifidobacterium | Faecalibacterium | Gemella | Haemophilus | Lachnospiraceae | Mitsuokella | Oscillospira | Prevotella | Pseudomonas | Rikenellaceae | Ruminococcus | Streptococcus
Endometriosis 0.0146 8 (0.02) : Acinetobacter | Enterobacteriaceae | Flavobacterium | Prevotella | Pseudomonas | Shigella | Sphingomonas | Streptococcus 4 (0.01) : Dialister | Gemella | Megasphaera | Prevotella
Wiskott-Aldrich syndrome 0.0146 1 (0.00) : Shigella 5 (0.03) : Alistipes | Bacteroides | Faecalibacterium | Parabacteroides | Phascolarctobacterium
Hirschsprung's disease 0.0144 4 (0.02) : Actinomyces | Escherichia | Prevotella | Pseudomonas 2 (0.01) : Lachnospiraceae | Ruminococcaceae
Clonorchis sinensis infection 0.0143 4 (0.01) : Epulopiscium | Ruminococcus | Sphingomonas | TM7 4 (0.02) : Bacteroides | Enterobacter | Parabacteroides | Paraprevotella
Anovulation 0.0143 1 (0.00) : Prevotella 7 (0.03) : Anaerostipes | Lachnospiraceae | Lactococcus | Oscillospira | Rikenellaceae | Roseburia | Ruminococcus
Chronic fatigue syndrome 0.0142 1 (0.00) : Enterobacteriaceae 6 (0.03) : Asaccharobacter | Eubacterium | Holdemania | Ruminococcaceae | Ruminococcus | Turicibacter
Bacterial vaginosis 0.0142 14 (0.03) : Acinetobacter | Actinomyces | Citrobacter | Eggerthella | Enterococcus faecium | Fusobacterium nucleatum | Gardnerella vaginalis | Lachnospiraceae | Peptoniphilus | Peptostreptococcus | Prevotella | Streptococcus | Streptococcus anginosus | Veillonella 1 (0.00) : Lactobacillus
Reactive arthritis 0.0141 1 (0.00) : Pseudomonas 4 (0.02) : Blautia | Collinsella | Coprococcus | Roseburia
Fatigue 0.0141 1 (0.00) : Ruminococcus gnavus 4 (0.02) : Alistipes | Faecalibacterium prausnitzii | Roseburia hominis | Ruminococcus
Anorexia nervosa 0.0139 2 (0.01) : Enterobacteriaceae | Enterococcus 5 (0.02) : Clostridium | Clostridium coccoides group | Roseburia | Ruminococcus | Streptococcus
Systemic sclerosis 0.0136 6 (0.02) : Bifidobacterium | Burkholderia | Citrobacter | Fusobacterium | Lactobacillus | Prevotella 2 (0.00) : Clostridium | Faecalibacterium
Sickle cell disease 0.0136 1 (0.01) : Escherichia 4 (0.02) : Alistipes | Faecalibacterium | Prevotella | Subdoligranulum
Graves' orbitopathy 0.0135 0 (0.00) 7 (0.03) : Anaerostipes | Bacteroides massiliensis | Blautia | Collinsella | Eubacterium hallii | Eubacterium ventriosum | Ruminococcus
Myasthenia gravis 0.0134 4 (0.01) : Acidaminococcus | Acinetobacter | Escherichia | Streptococcus 6 (0.02) : Clostridium | Coriobacteriaceae | Eubacterium | Faecalibacterium prausnitzii | Lactobacillus | Paraprevotella
Chronic pancreatitis 0.0134 1 (0.00) : Shigella 6 (0.02) : Collinsella | Dorea | Erysipelotrichaceae | Faecalibacterium | Lachnospiraceae | Subdoligranulum
Tetratricopeptide repeat domain 7A deficiency 0.0130 3 (0.01) : Actinobacillus | Clostridium | Enterobacteriaceae 2 (0.01) : Oscillospira | Ruminococcaceae
Colon polyps 0.0130 6 (0.02) : Bacteroides fragilis | Bacteroides vulgatus | Eubacterium cylindroides | Faecalibacterium prausnitzii | Ruminococcus gnavus | Ruminococcus torques 2 (0.01) : Collinsella aerofaciens | Lactobacillus
Influenza A 0.0125 5 (0.02) : Acinetobacter | Actinomyces | Lactobacillus | Pseudomonas | Streptococcus 4 (0.01) : Gemella | Haemophilus | Neisseria | Streptococcus
Neuromyelitis optica 0.0123 5 (0.01) : Coprococcus | Flavobacterium | Prevotella melaninogenica | Shigella | Streptococcus 5 (0.01) : Blautia | Coprococcus | Faecalibacterium | Lachnospiraceae | Roseburia
Chronic Laryngitis 0.0122 2 (0.02) : Pseudomonas | Streptococcus 4 (0.01) : Helicobacter | Neisseria | Paenibacillus | Prevotella
Infective colitis 0.0121 0 (0.00) 4 (0.02) : Bifidobacterium | Blautia coccoides | Clostridium leptum | Faecalibacterium prausnitzii
Autoimmune Thyroid Disorders 0.0121 0 (0.00) 4 (0.02) : Akkermansia muciniphila | Bifidobacterium | Faecalibacterium prausnitzii | Lactobacillus
Otitis Media 0.0120 8 (0.02) : Actinobacillus | Eikenella | Fusobacterium | Haemophilus | Klebsiella | Prevotella | Streptococcus | Veillonella 1 (0.00) : Streptococcus
Osteoporosis 0.0118 5 (0.02) : Actinomyces | Blautia | Clostridium cluster XIVa | Eggerthella | Lactobacillus 1 (0.01) : Roseburia
Obstructive sleep apnea-hypopnea syndrome 0.0118 6 (0.02) : Fusobacterium | Haemophilus | Prevotella | Pseudomonas | Streptococcus | Veillonella 4 (0.00) : Bifidobacterium | Dialister | Oscillibacter | Ruminococcaceae
Invasive colorectal cancer 0.0118 3 (0.01) : Enterococcus | Fusobacterium | Fusobacterium nucleatum 3 (0.01) : Clostridiales | Desulfovibrio | Lactobacillus
Preterm birth 0.0115 5 (0.02) : Gardnerella vaginalis | Prevotella | Rothia | Streptococcus | Veillonella 3 (0.00) : Bacteroides | Bifidobacterium longum | Clostridium cluster IV
Chronic Rhinosinusitis 0.0109 4 (0.01) : Escherichia | Fusobacterium | Pseudomonas | Staphylococcus aureus 7 (0.01) : Bacteroides | Bacteroidetes | Clostridiales | Lachnospiraceae | Lactobacillus | Parabacteroides | Ruminococcaceae
Botulism 0.0108 2 (0.02) : Enterobacteriaceae | Proteobacteria 1 (0.01) : Firmicutes
Urolithiasis 0.0108 2 (0.02) : Enterobacteriaceae | Lachnospiraceae 1 (0.01) : Lactobacillus
Laryngeal carcinoma 0.0107 7 (0.02) : Burkholderia | Capnocytophaga | Fusobacterium | Peptostreptococcus | Prevotella | Proteus | Staphylococcus 2 (0.00) : Hallella | Streptococcus
Pancreatic head cancer 0.0107 4 (0.01) : Actinomyces | Fusobacterium | Peptostreptococcus | Rothia 3 (0.01) : Haemophilus | Paraprevotella | Pasteurellaceae
T2D with hypertension 0.0106 2 (0.01) : Aeromonas | Ruminococcus 4 (0.01) : Enterobacter | Klebsiella | Lactobacillus | Megasphaera
Cutaneous burn 0.0104 3 (0.01) : Enterococcus | Flavobacterium | Staphylococcus 2 (0.01) : Lactobacillus | Streptococcus
Oral lichen planus 0.0099 4 (0.01) : Candida | Fusobacterium | Fusobacterium nucleatum | Prevotella 6 (0.01) : Bacteroides | Haemophilus | Neisseria | Streptococcus | Streptococcus salivarius | Trichosporon
Hyperthyroidism 0.0099 1 (0.01) : Enterococcus 2 (0.01) : Bifidobacterium | Lactobacillus
Liver fibrosis 0.0099 2 (0.01) : Prevotella | Sphingomonas 3 (0.01) : Coriobacteriaceae | Lachnospiraceae | Ruminococcaceae
Shiga Toxin-producing E. coli infection 0.0099 1 (0.01) : Lactobacillales 2 (0.01) : Bifidobacterium longum | Clostridiales
Posttreatment Lyme disease syndrome 0.0099 1 (0.01) : Blautia 2 (0.01) : Bacteroides | Roseburia
Psychogenic erectile dysfunction 0.0097 0 (0.00) 4 (0.02) : Blautia | Lachnospiraceae | Prevotella | Roseburia
Alcoholic cirrhosis 0.0096 2 (0.00) : Staphylococcus | Streptococcus mutans 4 (0.02) : Alistipes | Dialister | Paraprevotella | Prevotella
Tongue cancer 0.0093 4 (0.02) : Actinomyces | Enterococcus | Rothia | Streptococcus 3 (0.00) : Gemella | Leptosphaeria | Prevotella
Transient Ischemic Attack 0.0092 2 (0.00) : Lactobacillus | Proteobacteria 4 (0.02) : Bacteroides | Faecalibacterium | Paraprevotella | Prevotella
Liver transplant 0.0091 0 (0.00) 3 (0.02) : Bifidobacterium | Faecalibacterium prausnitzii | Lactobacillus
Wilson's Disease 0.0091 0 (0.00) 3 (0.02) : Phascolarctobacterium | Prevotella | Roseburia
Rectal Carcinoma 0.0089 1 (0.00) : Odoribacter 4 (0.02) : Bacillus | Bifidobacterium | Lactobacillus | Pseudomonas
Kawasaki disease 0.0088 5 (0.02) : Blautia | Clostridium | Coprococcus | Roseburia hominis | Ruminococcus 0 (0.00)
Extrinsic black dental staining 0.0088 5 (0.02) : Actinomyces | Capnocytophaga | Fusobacterium | Haemophilus | Peptostreptococcus 0 (0.00)
Primary Open-Angle Glaucoma 0.0087 3 (0.02) : Enterobacteriaceae | Escherichia coli | Streptococcus 0 (0.00)
Chronic Rhinosinusitis with cystic fibrosis 0.0087 3 (0.02) : Finegoldia | Peptoniphilus | Streptococcus 0 (0.00)
Protracted bacterial bronchitis 0.0087 5 (0.01) : Bifidobacterium | Enterococcus | Haemophilus | Prevotella | Pseudomonas 2 (0.01) : Lactobacillus | Lactococcus
Breast cancer 0.0084 6 (0.01) : Actinomyces | Caulobacteriaceae | Enterobacteriaceae | Fusobacterium | Salmonella enterica | Staphylococcus 4 (0.01) : Clostridiales | Lactococcus | Prevotella | Streptococcus
Primary liver cancer 0.0084 4 (0.01) : Enterococcus | Escherichia coli | Ruminococcus gnavus | Shigella 1 (0.00) : Lactococcus
Seminal hyperviscosity 0.0082 2 (0.01) : Klebsiella | Pseudomonas 1 (0.01) : Lactobacillus
Oligoasthenoteratozoospermia 0.0082 2 (0.01) : Klebsiella | Pseudomonas 1 (0.01) : Lactobacillus
Overactive bladder 0.0080 2 (0.00) : Proteus | Staphylococcus 5 (0.01) : Dialister | Enterococcus | Lactobacillus | Lactococcus | Prevotella
H7N9 0.0080 2 (0.00) : Fusobacterium | Pseudomonas 2 (0.01) : Haemophilus | Pasteurellaceae
Osmotic diarrhea 0.0079 1 (0.01) : Acinetobacter 2 (0.01) : Alistipes | Holdemania
Gingivitis 0.0079 1 (0.01) : Streptococcus 2 (0.01) : Prevotella | Streptococcus
Chronic mucocutaneous candidiasis 0.0079 1 (0.01) : Acinetobacter 2 (0.01) : Fusobacteria | Prevotella
Hyper IgE syndrome 0.0079 1 (0.01) : Acinetobacter 2 (0.01) : Fusobacteria | Prevotella
Iron-deficiency anaemia 0.0076 3 (0.01) : Enterococcus | Lactobacillus | Pseudomonas 1 (0.00) : Neisseria
Depression 0.0074 1 (0.00) : Lactobacillus 3 (0.01) : Bacteroides fragilis | Coprococcus | Dialister
Pneumonia 0.0074 3 (0.01) : Prevotella | Rothia | Veillonella 1 (0.00) : Streptococcus
Prediabetes 0.0074 1 (0.00) : Streptococcus 2 (0.01) : Akkermansia muciniphila | Clostridium
Allergic asthma 0.0074 1 (0.00) : Bifidobacterium 2 (0.01) : Akkermansia muciniphila | Faecalibacterium prausnitzii
Radiation enteritis 0.0074 1 (0.00) : Prevotella 2 (0.01) : Bacteroides | Blautia
Head/Neck cancer 0.0073 3 (0.01) : Ruminococcus | Stenotrophomonas | Streptococcus anginosus 1 (0.00) : Lachnospiraceae
Mucosa-associated lymphoid tissue lymphoma 0.0073 2 (0.00) : Clostridium | Rothia 5 (0.01) : Bacteroides | Clostridium | Lactobacillus | Parabacteroides | Rhodobacter
Vaginal Chlamydiosis 0.0071 7 (0.01) : Collinsella | Gardnerella vaginalis | Lactobacillus | Prevotella | Pseudomonas | Streptococcus | Veillonella 1 (0.00) : Stenotrophomonas
Necrotizing enterocolitis 0.0070 4 (0.01) : Citrobacter | Clostridium butyricum | Enterococcus | Escherichia coli 1 (0.00) : Klebsiella
Halitosis 0.0069 4 (0.00) : Capnocytophaga | Peptostreptococcus | Prevotella | TM7 4 (0.01) : Gemella | Moryella | Streptococcus | Streptococcus salivarius
Anti-N-methyl-D-aspartate receptor encephalitis 0.0069 2 (0.01) : Fusobacterium | Streptococcus 1 (0.01) : Clostridiales
Atrial fibrilation 0.0068 0 (0.00) 3 (0.01) : Barnesiellaceae | Lachnobacterium | Mitsuokella
Aphthous stomatitis 0.0068 0 (0.00) 3 (0.01) : Akkermansia | Clostridium | Veillonellaceae
Pressure ulcers 0.0068 5 (0.01) : Anaerotruncus | Enterococcus | Parabacteroides distasonis | Ruminococcus gnavus | Staphylococcus aureus 1 (0.00) : Ruminococcus bromii
Recurrent miscarriage 0.0067 2 (0.01) : Prevotella | Streptococcus 1 (0.00) : Lactobacillus
Sicca syndrome 0.0067 6 (0.01) : Actinomyces | Fusobacterium nucleatum | Peptostreptococcus | Prevotella | Streptococcus mutans | Streptococcus salivarius 2 (0.00) : Neisseria | Streptococcus
Acute lymphoblastic leukemia 0.0067 1 (0.00) : Bacteroides fragilis 5 (0.01) : Alistipes | Bifidobacterium | Faecalibacterium | Prevotella | Veillonellaceae
Cervical cancer 0.0066 5 (0.01) : Gardnerella vaginalis | Morganella | Peptostreptococcus anaerobius | Proteus | Ruminococcus 1 (0.00) : Phascolarctobacterium
Idiopathic REM Sleep Behavior Disorder 0.0065 2 (0.01) : Anaerotruncus | Eggerthella 3 (0.01) : Megasphaera | Mitsuokella | Prevotella
Pregnancy 0.0062 2 (0.00) : Proteobacteria | Streptococcus 6 (0.01) : Dialister | Megasphaera | Moryella | Prevotella | Ruminococcaceae | Streptococcus
Cavernous angioma 0.0061 0 (0.00) 2 (0.01) : Bifidobacterium adolescentis | Faecalibacterium prausnitzii
Cirrhosis with pneumonia 0.0061 2 (0.01) : Actinomyces | Lachnospiraceae 1 (0.01) : Streptococcus
Frailty 0.0061 0 (0.00) 2 (0.01) : Faecalibacterium prausnitzii | Lachnospiraceae
Diarrhea 0.0061 0 (0.00) 2 (0.01) : Bifidobacterium | Enterococcus
Melanoma 0.0056 2 (0.01) : Bifidobacterium | Enterococcus faecium 1 (0.01) : Faecalibacterium
Barrett's oesophagus 0.0056 3 (0.01) : Fusobacterium | Sphingomonas | Veillonella 2 (0.00) : Gemella | Streptococcus
Idiopathic central precocious puberty 0.0055 3 (0.00) : Acinetobacter | Coprococcus | Pseudomonas 1 (0.01) : Ruminococcus gnavus
Dry eye syndrom 0.0054 2 (0.00) : Prevotella | Veillonella 2 (0.01) : Faecalibacterium | Subdoligranulum
Dandruff 0.0054 5 (0.01) : Candida | Malassezia restricta | Propionibacterium acnes | Pseudomonas | Staphylococcus 0 (0.00)
Cleft palate 0.0054 1 (0.01) : Streptococcus 1 (0.00) : Bacillus
Intrahepatic Cholangiocarcinoma 0.0054 2 (0.01) : Actinomyces | Lactobacillus 1 (0.00) : Lachnospira
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy 0.0054 2 (0.01) : Barnesiellaceae | Odoribacter 1 (0.00) : Megasphaera
Cervicitis 0.0052 2 (0.01) : Eggerthella | Prevotella 0 (0.00)
Vulvar vestibulitis syndrome 0.0052 2 (0.01) : Enterococcus | Streptococcus 0 (0.00)
Silicosis 0.0052 1 (0.00) : Lachnospiraceae 4 (0.01) : Bacteroides | Bifidobacterium | Blautia | Subdoligranulum
Cervical intraneoplasia 0.0052 2 (0.01) : Lactobacillus | Staphylococcus 0 (0.00)
Pemphigus vulgaris 0.0052 2 (0.01) : Collinsella | Coprococcus 0 (0.00)
Infant colic 0.0050 1 (0.00) : Acinetobacter 1 (0.01) : Bifidobacterium
Laryngotracheal stenosis 0.0050 1 (0.00) : Acinetobacter 1 (0.01) : Prevotella
Diabetic nephropathy 0.0050 1 (0.00) : Shigella 1 (0.01) : Prevotella
T2D with hypertension and hyperlipidemia 0.0049 1 (0.01) : Prevotella 1 (0.00) : Gemella
Autoimmune polyendocrine syndrome type 1 0.0049 1 (0.00) : Fusobacterium nucleatum 6 (0.01) : Bacteroides | Bacteroidetes | Desulfovibrio | Lachnospiraceae | Mitsuokella | Ruminococcaceae
Edentulism 0.0046 6 (0.01) : Bacteroides ureolyticus | Capnocytophaga | Peptostreptococcus | Streptococcus anginosus | Streptococcus salivarius | Veillonella dispar 2 (0.00) : Dialister invisus | Peptococcus
Acute fatty liver 0.0046 2 (0.00) : Acinetobacter | Enterococcus 2 (0.00) : Adlercreutzia | Blautia
Excessive vomiting 0.0046 2 (0.00) : Acinetobacter | Enterococcus 2 (0.00) : Adlercreutzia | Blautia
Bleeding gum 0.0046 2 (0.01) : Fusobacterium | Prevotella 2 (0.00) : Haemophilus | Streptococcus
Chronic prostatitis - Chronic pelvic pain syndrome 0.0045 0 (0.00) 3 (0.01) : Coriobacteriaceae | Mogibacterium | Prevotella
Urgency urinary incontinence 0.0044 3 (0.01) : Gardnerella vaginalis | Staphylococcus | Streptococcus anginosus 1 (0.00) : Lactobacillus
Hemodialysis with Normal Weight Obesity 0.0044 1 (0.00) : Lachnobacterium 2 (0.00) : Coprococcus | Faecalibacterium prausnitzii
Multiple system atrophy 0.0043 3 (0.01) : Bacteroides fragilis | Lactobacillus | Roseburia hominis 2 (0.00) : Blautia | Haemophilus
Alopecia universalis 0.0042 2 (0.00) : Lachnospiraceae | Parabacteroides distasonis 2 (0.00) : Flavonifractor plautii | Turicibacter sanguinis
Clostridium difficile associated disease 0.0041 2 (0.01) : Candida albicans | Proteobacteria 1 (0.00) : Bacteroidetes
Idiopathic infertility 0.0041 2 (0.01) : Gardnerella vaginalis | Veillonella 1 (0.00) : Fusobacteria
Denture Stomatitis 0.0039 1 (0.01) : Fusobacterium 0 (0.00)
Giardia intestinalis infection 0.0039 1 (0.01) : Prevotella 0 (0.00)
Nasolacrimal duct obstruction 0.0039 1 (0.01) : Staphylococcus 0 (0.00)
Oropharyngeal cancer 0.0039 2 (0.01) : Haemophilus parainfluenzae | Streptococcus anginosus 0 (0.00)
Hypopharyngeal cancer 0.0039 2 (0.01) : Haemophilus parainfluenzae | Veillonella parvula 0 (0.00)
Atrophic gastritis 0.0038 1 (0.00) : Enterobacteriaceae 3 (0.00) : Faecalibacterium | Lachnospiraceae | Roseburia
Oral potentially malignant disorder 0.0038 5 (0.01) : Fusobacterium nucleatum | Parvimonas micra | Prevotella melaninogenica | Streptococcus salivarius | Veillonella parvula 1 (0.00) : Streptococcus mitis
Intestinal metaplasia 0.0037 2 (0.00) : Flavobacterium | Streptococcus 2 (0.00) : Bacillus | Paenibacillus
Viral respiratory tract infection 0.0036 1 (0.00) : Staphylococcus aureus 1 (0.01) : Prevotella
Hirschsprung-associated enterocolitis 0.0035 1 (0.00) : Proteobacteria 1 (0.00) : Firmicutes
Stomach cancer 0.0035 1 (0.00) : Ruminococcus 1 (0.00) : Oscillibacter
Diaper dermatitis 0.0035 2 (0.00) : Ruminococcus gnavus | Staphylococcus aureus 2 (0.00) : Bifidobacterium longum | Clostridium perfringens
Kidney stone with hypertension 0.0035 2 (0.00) : Anaerovorax | Lactobacillus 4 (0.00) : Bilophila | Clostridium cluster IV | Phascolarctobacterium | Stenotrophomonas
Cystic fibrosis exacerbation 0.0034 0 (0.00) 3 (0.01) : Haemophilus | Pseudomonas | Streptococcus
Tuberculosis 0.0032 3 (0.01) : Parvimonas micra | Prevotella melaninogenica | Streptococcus anginosus 0 (0.00)
Eosinophilic esophagitis 0.0032 1 (0.00) : Haemophilus 2 (0.00) : Lactobacillus | Streptococcus
Opisthorchis felineus infection 0.0031 4 (0.01) : Faecalibacterium prausnitzii | Haemophilus parainfluenzae | Parabacteroides distasonis | Veillonella dispar 0 (0.00)
Obesity (Diet induced) 0.0030 0 (0.00) 1 (0.01) : Akkermansia muciniphila
Rhinovirus infection 0.0030 0 (0.00) 1 (0.01) : Neisseria
Undernourishment 0.0030 0 (0.00) 1 (0.01) : Bacteroidetes
Chronic stress 0.0030 0 (0.00) 1 (0.01) : Phascolarctobacterium
Diverticular disease 0.0028 1 (0.00) : Enterobacteriaceae 1 (0.00) : Bacteroides fragilis
Chronic rhinosinusitis with nasal polyps 0.0027 1 (0.00) : Haemophilus parainfluenzae 1 (0.00) : Bifidobacterium longum
Prostate cancer 0.0026 2 (0.01) : Escherichia | Propionibacterium acnes 0 (0.00)
Alopecia areata 0.0026 2 (0.01) : Propionibacterium acnes | Proteobacteria 0 (0.00)
Bronchiectasis 0.0025 1 (0.00) : Pseudomonas 1 (0.00) : Haemophilus
Pulmonary arterial hypertension 0.0025 1 (0.00) : Ruminococcus gnavus 3 (0.00) : Akkermansia muciniphila | Coprococcus eutactus | Subdoligranulum
Periodontal disease 0.0023 3 (0.00) : Fusobacterium nucleatum | Parvimonas micra | Prevotella 3 (0.00) : Haemophilus | Mitsuokella | Streptococcus
Genitourinary lichen sclerosus 0.0023 1 (0.00) : Lactobacillus 1 (0.00) : Dialister
Human papilloma virus infection 0.0022 2 (0.00) : Eggerthella | Gardnerella vaginalis 0 (0.00)
Oral leukoplakia 0.0022 2 (0.00) : Candida albicans | Fusobacterium nucleatum 0 (0.00)
Granulomatosis with polyangiitis 0.0022 2 (0.00) : Staphylococcus | Staphylococcus aureus 0 (0.00)
Adolescent idiopathic scoliosis 0.0020 0 (0.00) 2 (0.00) : Bacteroides fragilis | Phascolarctobacterium
Urinary stone disease 0.0019 1 (0.00) : Lactobacillales 0 (0.00)
Recurrent tonsillitis 0.0019 2 (0.00) : Prevotella melaninogenica | Streptococcus intermedius 1 (0.00) : Streptococcus salivarius
Conjunctival scarring 0.0019 1 (0.00) : Streptococcus 0 (0.00)
Exacerbations of idiopathic pulmonary fibrosis 0.0019 1 (0.00) : Stenotrophomonas 0 (0.00)
Seborrheic dermatitis 0.0019 1 (0.00) : Staphylococcus 2 (0.00) : Bacteroides | Pseudomonas
Azoospermia 0.0016 0 (0.00) 3 (0.00) : Coprococcus | Desulfovibrio | Helicobacter
Gout 0.0015 0 (0.00) 1 (0.00) : Faecalibacterium prausnitzii
Neuro-Behcet's disease 0.0015 0 (0.00) 1 (0.00) : Lachnospiraceae
Neisseria gonorrhoeae infection 0.0015 0 (0.00) 1 (0.00) : Pseudomonas
Refractory celiac disease 0.0013 1 (0.00) : Streptococcus intermedius 0 (0.00)
Hepatitis B associated liver failure 0.0012 1 (0.00) : Burkholderia 1 (0.00) : Bacteroides fragilis

[Overlap Factors (Causality ?)]

FactorOverlapCommon increased OrganismCommon decreased Organism
Exposure to Glyphosate 0.0192 5 (0.03) : Actinomyces | Fusobacterium | Prevotella | Turicibacter | Veillonella 2 (0.01) : Lactobacillus | Streptococcus
Antibiotic Therapy 0.0124 3 (0.02) : Enterobacteriaceae | Lactobacillales | Proteobacteria 1 (0.00) : Clostridiales
Protein powder consumption 0.0121 0 (0.00) 6 (0.02) : Bifidobacterium longum | Blautia | Coprococcus | Firmicutes | Lachnospiraceae | Roseburia
Oral administration of Metformin 0.0113 1 (0.00) : Ruminococcus 5 (0.02) : Coriobacteriaceae | Dehalobacterium | Dorea | Lactobacillus | Roseburia
Aging 0.0099 1 (0.01) : Proteobacteria 2 (0.01) : Bifidobacterium | Faecalibacterium
Mediterranean diet 0.0092 2 (0.01) : Faecalibacterium prausnitzii | Lachnospiraceae 2 (0.01) : Ruminococcus gnavus | Ruminococcus torques
Cannabis smoking 0.0082 2 (0.01) : Actinomyces | Streptococcus 1 (0.01) : Neisseria
Maternal Antibiotic Exposure 0.0080 1 (0.00) : Proteobacteria 2 (0.01) : Bacteroidetes | Bifidobacterium
Heat Stress 0.0080 1 (0.00) : Clostridium 2 (0.01) : Bacteroides | Lactobacillus
High Socio-economic status 0.0069 2 (0.01) : Anaerostipes | Lachnospiraceae 1 (0.01) : Bacteroides
High-fat diet 0.0061 0 (0.00) 4 (0.01) : Akkermansia | Bacteroidetes | Clostridiales | Ruminococcaceae
Grape powder consumption 0.0061 0 (0.00) 2 (0.01) : Bifidobacterium | Dialister
Sugar intake 0.0050 1 (0.00) : Bacteroides fragilis 1 (0.01) : Lactobacillus
High salt diet 0.0050 1 (0.00) : Bifidobacterium 1 (0.01) : Lactobacillus
High Water drinking 0.0040 0 (0.00) 2 (0.01) : Bacteroides | Odoribacter
Consumption of Coffee 0.0039 3 (0.01) : Bifidobacterium | Blautia | Odoribacter 0 (0.00)
Alcohol administration 0.0030 0 (0.00) 1 (0.01) : Akkermansia
Eating appel 0.0030 0 (0.00) 1 (0.01) : Firmicutes
Low FODMAP diet 0.0030 0 (0.00) 1 (0.01) : Bifidobacterium

[Reverse Overlap Factors (Curability ?)]

FactorOverlapIncrease decreased Org/DisDecrease increased Org/Dis
Oral administration of Metformin 0.0215 7 (0.04) : Akkermansia muciniphila | Bacteroidetes | Clostridiales | Lactococcus | Megasphaera | Ruminococcaceae | Ruminococcus 1 (0.00) : Lactobacillus
Consumption of Coffee 0.0211 7 (0.04) : Alistipes | Bifidobacterium | Blautia | Dialister | Faecalibacterium | Odoribacter | Roseburia 0 (0.00)
Mediterranean diet 0.0157 3 (0.02) : Faecalibacterium prausnitzii | Lachnospiraceae | Roseburia 2 (0.01) : Ruminococcus gnavus | Ruminococcus torques
High Socio-economic status 0.0155 4 (0.03) : Anaerostipes | Eubacterium | Faecalibacterium | Lachnospiraceae 0 (0.00)
Exposure to Glyphosate 0.0126 3 (0.01) : Parabacteroides | Prevotella | Turicibacter 3 (0.01) : Lactobacillus | Rothia | Streptococcus
Sugar intake 0.0108 2 (0.02) : Akkermansia muciniphila | Bacteroides fragilis 1 (0.01) : Lactobacillus
High salt diet 0.0108 2 (0.02) : Akkermansia | Bifidobacterium 1 (0.01) : Lactobacillus
Heat Stress 0.0093 2 (0.02) : Clostridium | Oscillospira 1 (0.00) : Lactobacillus
Protein powder consumption 0.0093 1 (0.01) : Bacteroidetes 4 (0.01) : Blautia | Coprococcus | Lachnospiraceae | Lactobacillales
High Water drinking 0.0079 1 (0.01) : Dorea 2 (0.01) : Odoribacter | Peptostreptococcus
Eating appel 0.0078 2 (0.02) : Akkermansia | Bacteroidetes 0 (0.00)
Low FODMAP diet 0.0069 1 (0.01) : Bacteroides 1 (0.01) : Bifidobacterium
Curcumin Supplementation 0.0061 0 (0.00) 2 (0.01) : Escherichia | Shigella
High-fat diet 0.0039 1 (0.01) : Firmicutes 0 (0.00)
Oral administration of Abiraterone acetate 0.0039 1 (0.01) : Akkermansia muciniphila 0 (0.00)
Maternal Antibiotic Exposure 0.0035 1 (0.00) : Firmicutes 1 (0.00) : Bifidobacterium
Probiotic (Bifidobacter and Lactobacilus) 0.0030 0 (0.00) 1 (0.01) : Enterobacteriaceae
Grape powder consumption 0.0025 1 (0.00) : Akkermansia 1 (0.00) : Bifidobacterium
Aging 0.0015 0 (0.00) 1 (0.00) : Bifidobacterium
Cannabis smoking 0.0013 1 (0.00) : Streptococcus 0 (0.00)

Common References