Disease ⇒ Critically ill conditions {40000168} Record Keys Type:Disease Parent:[ ] Definition:Critically ill conditions Details Initialisation date:2021-09-13 Other Terms:[ ] Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - The critical ill patients had about 10,000 times lower total anaerobes, including Bifidobacterium and Lactobacillus, and 100 times higher Staphylococcus. - Total organic acids, acetic acid, and especially butyric acid derived from gut microbiota are significantly decreased. - The gut microbiota begins to change within the first 6 h. - 17 species of bacteria, including Clostridiales, induce regulatory T cells. - ICU patients are significantly lower in the proportions of the class Clostridia. - IFN-γ-producing CD8 + cells were induced by 11 species of bacteria included in the phyla Bacteroidetes, Firmicutes, and Fusobacterium. [1.2] References Notes[ ]
