MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Urinary stone disease {40000161}

Record Keys


Definition:
Urinary stone disease
Class:[  ]

Details


Other Terms:
Urinary Calculi, Nephrolithiasis, Stones, Urolithiasis
Authoring date:
2020-09-06

Links


Meta Information


ICD:[  ]
Category:
Renal
MedDra ID:[  ]
MedDra Level:[  ]

Notes


[  ]

Shared Notes


  • [1.1
    - Lactobacillus may inhibit stone growth. However, our multi-omics integration strongly points to three unknown metabolites.
    - The bacterium Oxalobacter formigenes uses oxalate as a carbon and energy source for growth, is negatively associated with both USD and urinary oxalate, is sensitive to common antibiotics, and can reduce urinary oxalate when administered orally as a probiotic, all of which implicates loss of function dysbiosis associated with this species and calcium oxalate stone formation.

Common References