Disease ⇒ Immunotherapy-induced colitis {40000144} Record Keys Type:Disease Parent:[ ] Definition:Immunotherapy-induced colitis Details Initialisation date:0000-00-00 Other Terms:[ ] Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - Dietary prebiotics, which can be metabolized by bacteria to produce #Butyrate, can be an intriguing new investigational approach to prevent immunotherapy-induced colitis and lead to improved patient outcomes. - #Butyrate is a gut-microbiome-derived, anti-inflammatory metabolite that could be protective against ICI colitis, based on data from other forms of colitis. - #Dietary prebiotic starches that can increase #Butyrate production are a promising method of microbial manipulation that could be used to mitigate ICI colitis.References Notes[ ]
