HTN , HT, high blood pressure (HBP)
- Faecalibacterium, Oscillibacter, Roseburia, Bifidobacterium, Coprococcus, and Butyrivibrio, which were enriched in healthy controls, declined in pHTN and HTN patients.
- Prevotella copri thrives in a pro-inflammatory environment.
- The superoxide reductase and phosphoadenosine phosphosulphate reductase encoded by Prevotella copri may favor the development of inflammation.
- Colonization with Prevotella copri enhances body weight loss and exacerbates epithelial inflammation in colitis mouse model.
- The enterotype dominated by Prevotella was enriched with pHTN and HTN populations.
- Prevotella was overrepresented in individuals with pHTN and HTN.
- Stearic acid, an important metabolite in HTN, is positively linked to Prevotella.
- CAGs and species taxonomic annotated to Prevotella were the common microbial characteristics of pHTN and HTN, and contributed a lot to classification of HTN.
- Prevotella may play an essential role in HTN, probably by triggering the inflammatory response.
- Higher levels of the genus Ruminococcus were linked with increased risk of high blood pressure. (3)
- Elevated putative succinate-producing bacteria and acetate-producing bacteria were associated with lower and higher mean arterial pressure in mouse, respectively
- Prevotella and Klebsiella were overrepresented in individuals with pHTN or HTN.
- There was a positive association between 9,10-dichloro-octadecanoic acid (stearic acid) and microflora including Klebsiella, Prevotella, and Enterbacter, which were all overrepresented in HTN.
- In HTN microbial richness and diversity are decreased with Prevotella-dominated gut enterotype.
- Bacteroidetes (Odoribacter and Alistipes genera), often contribute to the overall butyrogenic pool. SCFA-producing bacteria may affect blood pressure by direct effects of SCFA on vasodilation or through plasminogen activator inhibitor-1 (PAI-1)
- Nitrate-rich supplements, in turn, stimulate nitrate reduction by the oral microbiota resulting in a lowering of blood pressure.
- [1.1] DUBLICATE_2_Gut microbiota dysbiosis contributes to the development of hypertension  
- [1.2] Alterations of the gut microbiome in hypertension  
- [1.3] DUBLICATE_1_Gut microbiota dysbiosis contributes to the development of hypertension  
- [1.4] Hypertension is associated with intestinal microbiota dysbiosis and inflammation in a Brazilian population  
- [1.5] Molecular characterization of alterations in the intestinal microbiota of patients with grade 3 hypertension  
- [1.6] Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure  
- [1.7] Sleep fragmentation increases blood pressure and is associated with alterations in the gut microbiome and fecal metabolome in rats  [Research] 
- [1.8] Gut microbiota dysbiosis contributes to the development of hypertension  [Report] 
- [1.9] Increased Systolic and Diastolic Blood Pressure Is Associated With Altered Gut Microbiota Composition and Butyrate Production in Early Pregnancy  [Research] 
- [1.10] Isolation and Characterization of Nitrate-Reducing Bacteria as Potential Probiotics for Oral and Systemic Health  [Research]